FlyBase Allele Report: Dmel\dom[7]

General Information

Symbol

Dmel\dom⁷

Species

D. melanogaster

Name

FlyBase ID

FBal0123001

Feature type

allele

Associated gene

Dmel\dom

Associated Insertion(s)

P{lacW-Δ7.R}dom⁷

Carried in Construct

Key Links

Allele class

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Ruhf et al., 2001)

Progenitor genotype

dom^k08108

(Ruhf et al., 2001)

Associated Insertion(s)

P{lacW-Δ7.R}dom⁷

Cytology

Description

Internal deletion of P{lacW} of P{lacW}dom^k08108 progenitor, inactivating the w^+mC allele.

(Ruhf et al., 2001)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female sterile (with dom⁹)

(Eissenberg et al., 2005)

female sterile (with dom¹⁰)

(Eissenberg et al., 2005)

female sterile | recessive

(Ruhf et al., 2001)

male fertile

(Ruhf et al., 2001)

partially lethal (with dom⁹)

(Eissenberg et al., 2005)

partially lethal (with dom¹⁰)

(Eissenberg et al., 2005)

partially lethal - majority die | recessive

(Ruhf et al., 2001)

visible (with dom¹⁰)

(Eissenberg et al., 2005)

Phenotype Manifest In

wing

(Ruhf et al., 2001)

wing (with dom¹⁰)

(Eissenberg et al., 2005)

Detailed Description

Statement

Reference

Lethality acts during pupal and adult stages. There are no clear larval defects. Surviving adults are female-sterile but male fertile. Wings are often abnormal with crumpled, held-out phenotypes.

(Ruhf et al., 2001)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

dom¹⁰/dom⁷ has partially lethal phenotype, suppressible | partially by Hsap\SRCAP^{Chi.Tag:polyHis}

(Eissenberg et al., 2005)

dom⁹/dom⁷ has partially lethal phenotype, suppressible | partially by Hsap\SRCAP^{Chi.Tag:polyHis}

(Eissenberg et al., 2005)

dom¹⁰/dom⁷ has female sterile phenotype, suppressible by Hsap\SRCAP^{Chi.Tag:polyHis}

(Eissenberg et al., 2005)

dom⁹/dom⁷ has female sterile phenotype, suppressible by Hsap\SRCAP^{Chi.Tag:polyHis}

(Eissenberg et al., 2005)

NOT suppressed by

Statement

Reference

dom¹⁰/dom⁷ has female sterile phenotype, non-suppressible by Hsap\SRCAP^{K649R.Chi.Tag:polyHis}

(Eissenberg et al., 2005)

dom⁹/dom⁷ has female sterile phenotype, non-suppressible by Hsap\SRCAP^{K649R.Chi.Tag:polyHis}

(Eissenberg et al., 2005)

dom¹⁰/dom⁷ has partially lethal phenotype, non-suppressible by Hsap\SRCAP^{K649R.Chi.Tag:polyHis}

(Eissenberg et al., 2005)

dom⁹/dom⁷ has partially lethal phenotype, non-suppressible by Hsap\SRCAP^{K649R.Chi.Tag:polyHis}

(Eissenberg et al., 2005)

Enhancer of

Statement

Reference

dom⁷ is an enhancer of visible phenotype of N^nd-1

(Eissenberg et al., 2005)

Other

Statement

Reference

Hsap\SRCAP^{Chi.Tag:polyHis}, dom¹⁰/dom⁷ has female fertile phenotype

(Eissenberg et al., 2005)

Hsap\SRCAP^{Chi.Tag:polyHis}, dom⁹/dom⁷ has female fertile phenotype

(Eissenberg et al., 2005)

Phenotype Manifest In

Enhancer of

Statement

Reference

dom⁷ is an enhancer of wing margin phenotype of N^nd-1

(Eissenberg et al., 2005)

Additional Comments

Genetic Interactions

Statement

Reference

dom⁷ enhances the wing nicking phenotype of N^nd-1.

(Eissenberg et al., 2005)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

dom⁷

(Eissenberg et al., 2005)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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