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General Information
Symbol
Dmel\Hsc70-4Δ16
Species
D. melanogaster
Name
FlyBase ID
FBal0124178
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

A deletion removes the first exon of Hsc70-4. Deletion spans +1 to +1369.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

TR-avidin update is blocked in homozygous Hsc70-4Δ16 cells, resulting in a decrease in both surface-bound and internalised tracer.

Flow cytometric analysis of mosaic wing imaginal discs reveals an increased cell size and increased G2 population in Hsc70-4Δ16 mutant cells, relative to wild-type. This effects are acutely dosage-sensitive, as Hsc70-4Δ16/+ heterozygous cells are also larger than wild-type.

Homozygous larvae show sporadic but reduced muscle contractions.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Hsc70-4Δ16
Name Synonyms
Secondary FlyBase IDs
    References (3)