FB2026_02 , released June 18, 2026
Allele: Dmel\Gbs-70EBG02516
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General Information
Symbol
Dmel\Gbs-70EBG02516
Species
D. melanogaster
Name
FlyBase ID
FBal0124377
Feature type
allele
Associated gene
Dmel\Gbs-70E
Associated Insertion(s)
P{GT1}Gbs-70EBG02516
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(Kerekes et al., 2014, Kong et al., 2010)
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{GT1}Gbs-70EBG02516
Cytology
Description

Insertion in exon 1 of Gbs-70E.

(Kerekes et al., 2014)
Allele components
Component
Use(s)
Inserted element
P{GT1}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  alcohol use disorder
      CEA
      (Kong et al., 2010)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The lifespan of mutants is not significantly affected.

      The glycogen content of mutants is not significantly affected.

      (Kerekes et al., 2014)

      CG9238BG02516 flies show a significant increase in locomotor activity upon repeated ethanol exposure compared to controls, with little or no effect on initial ethanol-induced hyperactivity, sedation sensitivity or sedation tolerance compared to controls.

      (Kong et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      BG02516
      (Kong et al., 2010)
      CG9238BG02516
      Gbs-70EBG02516
      P-GT1
      (Kerekes et al., 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)