FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\tefuΔ11
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General Information
Symbol
Dmel\tefuΔ11
Species
D. melanogaster
Name
FlyBase ID
FBal0124386
Feature type
allele
Associated gene
Dmel\tefu
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
    Nature of the Allele
    Allele class

    hypomorphic allele - genetic evidence

    (Song et al., 2004)
    Mutagen
    Progenitor genotype
    Caused by aberration
    Df(3R)Hsc70-4Δ11
    Cytology
    Description

    Deletion breakpoint within tefu. The deletion removes the first 2 exons of tefu.

    (Song et al., 2004)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    deletion
    3R:15,241,876..15,243,541 [-]
    Comment:

    Imprecise excision of the EP(3)0859 P-element, deleting 1666 nucleotides, including the first 2 coding exons of tefu. Position of mutation on reference sequence inferred by FlyBase curator.

    (Song et al., 2004)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 1 )
        Disease
        Evidence
        References
        model of  ataxia telangiectasia
        CEA with Hsc70-4+t14
        (Song et al., 2004)
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Most tefuΔ11 homozygous flies (Df(3R)Hsc70-4Δ11 homozygotes in which the lack of Hsc70-4 function has been rescued by Hsc70-4+t14) show pupal lethality, although 12% eclose and are viable. These adult escapers do not survive for very long after eclosion. Escaper females lay a very small number of eggs that do not hatch.

        (Song et al., 2004)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        CG6535Δ11
        (Bronk et al., 2001)
        atmΔ11
        tefuΔ11
        Name Synonyms
        Secondary FlyBase IDs
          References (2)