FB2026_02 , released June 18, 2026
Allele: Dmel\E(To)1212
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General Information
Symbol
Dmel\E(To)1212
Species
D. melanogaster
Name
FlyBase ID
FBal0126605
Feature type
allele
Associated gene
E(To)12
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Jankovics et al., 2001)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      E(To)1212/E(To)12[+] is an enhancer of embryonic abdominal segment phenotype of Tm1el4/Tm1eg9, osk1

      (Jankovics et al., 2001)

      E(To)1212/E(To)12[+] is an enhancer of embryonic/first instar larval cuticle phenotype of Tm1el4/Tm1eg9, osk1

      (Jankovics et al., 2001)

      E(To)1212/E(To)12[+] is an enhancer of embryonic abdominal segment phenotype of Tm1el4/Tm1eg9, osk[+]/osk1

      (Jankovics et al., 2001)

      E(To)1212/E(To)12[+] is an enhancer of embryonic/first instar larval cuticle phenotype of Tm1el4/Tm1eg9, osk[+]/osk1

      (Jankovics et al., 2001)

      osk[+], osk1, E(To)1212, E(To)12[+] is an enhancer of embryonic/first instar larval cuticle phenotype of Tm1el4/Tm1eg9

      (Jankovics et al., 2001)
      Suppressor of
      Statement
      Reference

      E(To)1212/E(To)12[+] is a suppressor of germline cell phenotype of Tm1eg20/Tm1eg9

      (Jankovics et al., 2001)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Dominantly increases the penetrance of the "posterior group" phenotype of embryos derived from Tm1eg9 +/Tm1el4 osk1 females to 86.0%. Also enhances the frequency of embryos without cuticle in this background. Dominantly decreases the penetrance of the germ cell-less phenotype of flies derived from Tm1eg9/Tm1eg20 females to 31.7%.

      (Jankovics et al., 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: a dominant enhancer of the Tm1eg9 +/Tm1el4 osk1 phenotype. Separable from: a second lethal mutation on the 3rd chromosome.

      (Jankovics et al., 2001)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      E(To)12
      (Jankovics et al., 2001)
      E(To)1212
      Name Synonyms
      Secondary FlyBase IDs
        References (1)