FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\trnUAS.cMa
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General Information
Symbol
Dmel\trnUAS.cMa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Milan
FlyBase ID
FBal0127170
Feature type
allele
Associated gene
Dmel\trn
Associated Insertion(s)
Carried in Construct
P{UAS-trn.M}
Also Known As
UAS-trn
Key Links
Transgenic product class
wild_type
(Milan et al., 2001)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Milan et al., 2001)
Mutagen
in vitro construct
(Milan et al., 2001)
Progenitor genotype
Carried in construct
P{UAS-trn.M}
Cytology
Description

UAS regulatory sequences drove expression of trn.

(Milan et al., 2001)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
trn
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos that express trnScer\UAS.cMa under the control of Scer\GAL4twi.PG show normal development of the tracheal system.

      (Krause et al., 2006)

      Medially located somatic clones of trnScer\UAS.cMa; Scer\GAL4Act5C.PP cells in the wing disc adopt more rounded shapes at the control clones. When such clones were laterally located they were more elongated than medial clones, but still had much smoother borders than equivalently located wild-type control clones.

      (Milan et al., 2002)

      Fewer clones expressing trnScer\UAS.cMa under the control of Scer\GAL4Act5C.PP are recovered in the ventral compartment of the wing disc compared to the dorsal compartment. Twice as many clones are recovered at the dorsal/ventral boundary as would be expected if expression of caps had no affect on their distribution. Wing disc clones expressing trnScer\UAS.cMa under the control of Scer\GAL4Act5C.PP that bisect the nascent dorsal/ventral boundary (these clones are induced in the wing disc in the early 2nd instar before the dorsal/ventral boundary forms) are more compact in shape and have smoother borders compared to control clones and are often considerably smaller in the ventral compartment than the dorsal compartment. Cells in ventral clones in the wing disc expressing trnScer\UAS.cMa under the control of Scer\GAL4Act5C.PP extend processes towards the dorsal compartment.

      (Milan et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      trnScer\UAS.cMa suppresses the loss of laterally located somatic clones of salmScer\UAS.cdCa; Scer\GAL4Act5C.PP cells in late third instar wing discs.

      (Milan et al., 2002)

      The boundary between the dorsal and ventral cells is still irregular in apmd544/apUGO35 wing discs expressing trnScer\UAS.cMa under the control of Scer\GAL4ap-md544. Fewer clones expressing both capsScer\UAS.cSa and trnScer\UAS.cMa under the control of Scer\GAL4Act5C.PP are recovered in the ventral compartment of the wing disc compared to the dorsal compartment. Twice as many clones are recovered at the dorsal/ventral boundary as would be expected if expression of caps had no affect on their distribution. Co-expression of BacA\p35Scer\UAS.cHa in clones expressing both capsScer\UAS.cSa and trnScer\UAS.cMa under the control of Scer\GAL4Act5C.PP suppresses the overall loss of ventral clones but ventral clones are still overrepresented approximately 2-fold at the dorsal/ventral boundary. Wing disc clones expressing both capsScer\UAS.cSa and trnScer\UAS.cMa under the control of Scer\GAL4Act5C.PP that bisect the nascent dorsal/ventral boundary (these clones are induced in the wing disc in the early 2nd instar before the dorsal/ventral boundary forms) are more compact in shape and have smoother borders compared to control clones and are often considerably smaller in the ventral compartment than the dorsal compartment.

      (Milan et al., 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      trnScer\UAS.cMa
      trnUAS.cMa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Milan
      (Milan et al., 2001)
      Secondary FlyBase IDs
        References (5)