rg^KG02343 mutants exhibit significant memory impairment relative to wild-type flies at 3 minute, 30 minute and 3 hours after one-cycle training. This phenotype does not result from abnormal shock or odor avoidance.

rg^KG02343 flies exhibit a 3 hour memory deficit in the absence of cold shock. When cold shock is applied at the second hour after one-cycle training, rg^KG02343 mutants show a further reduced 3 hour memory. Interesting, this memory reduction is also seen in wild-type controls, indicating that the defective memory in rg^KG02343 mutants is part of labile memory.

24 hour memory is normal in rg^KG02343 mutants subjected to massed or spaced training. Single rg^KG02343 and rg¹/rg^KG02343 trans-heterozygotes display normal 24 hour memory after spaced training. Taken together, these results indicate that rg mutants have defective short-term memory but normal consolidated memory.