FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.
Mutants lack alpha and alpha' lobes of the mushroom bodies. The more intensively flies are trained, the less they remember; they show almost non memory 5 hours after spaced conditioning. Anasthesia resistant consolidated memory seems to be erased during a long term memory-specific training protocols.
Mutants are bang-sensitive, with a recovery period of 52 +/- 10 seconds and a refractory period of 510 +/- 30 seconds.
Mutant flies show a reduced seizure threshold (of 4.5 +/- 0.2 V) compared to wild type in response to high-frequency electrical stimulation.
1-hour, 3-hour, 24-hour (spaced training) and 24-hour (massed training) memory are normal in mutant flies. 3-hour memory is not reduced in mutant flies lacking either α α' or β β' lobes of the mushroom body. Long term memory (24-hour spaced training) is normal in the flies which have β β' lobes, but is completely abolished in flies which lack the α α' lobes (the long term memory defect is not caused by the fused β β' lobe defect which may be seen in these flies). 24-hour (massed training) memory is not reduced in flies lacking the α α' lobes.
cpo[+]/cpoEG1, easunspecified has bang sensitive | dominant phenotype