FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\verS147910
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General Information
Symbol
Dmel\verS147910
Species
D. melanogaster
Name
FlyBase ID
FBal0129273
Feature type
allele
Associated gene
Dmel\ver
Associated Insertion(s)
P{lacW}verS147910
Carried in Construct
Also Known As
ver2, l(3)S147910
Key Links
Genomic Maps

Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Raffa et al., 2010)
Mutagen
Delta2-3 transposase
(Deak et al., 1997)
Progenitor genotype
Associated Insertion(s)
P{lacW}verS147910
Cytology
Description

Insertion within the coding sequence.

(Raffa et al., 2010)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The mitotic cells from the brains of ver1/verS147910 and ver1/Df(3L)sex204 larvae show frequent telomeric associations. Both single telomeric associations (a single telomere associated with either its sister or a nonsister telomere) and double telomeric associations (a pair of sister telomeres associated with another pair) are seen. The mitotic cells from the brains of homozygous larvae show more frequent telomeric associations than those of ver1/verS147910 or ver1/Df(3L)sex204 larvae. Most of the telomeric associations seen in the homozygous larvae are double telomeric associations.

      (Raffa et al., 2010)

      (with Df(3L)iro-2) lethal lethal | recessive

      (Carre et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      verS147910/ver[+] is an enhancer of male semi-sterile phenotype of cav1/Df(3R)Exel6198, cavHipHop.GFP

      (Dubruille and Loppin, 2015)
      Other
      Statement
      Reference

      peo1, verS147910/ver[+] has abnormal mitotic cell cycle | larval stage phenotype

      (Cenci et al., 2015)
      Phenotype Manifest In
      Other
      Statement
      Reference

      peo1, verS147910/ver[+] has larval neuroblast phenotype

      (Cenci et al., 2015)

      peo1, verS147910/ver[+] has chromosome | larval stage phenotype

      (Cenci et al., 2015)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      peo1, verS147910 double heterozygosity leads to telomeric fusions in larval neuroblasts.

      (Cenci et al., 2015)

      The slightly reduced fertility of cavHipHop.T:Avic\GFP/Y;cav1/Df(3R)Exel6198 adult (cav1 rescue) males is moderately enhanced by combination with verS147910.

      The increased number of abnormal spermatid nuclei (showing chromatin bridges) characteristic for adult cavHipHop.T:Avic\GFP;cav1/Df(3R)Exel6198 males is strongly enhanced by combination with Df(3R)ms(3)K81-2 in homozygous or, to a lesser degree, in heterozygous state. Enhancement of the abnormal nuclear phenotype is also observed upon combination with single copy of HipHop1 as well as verS147910 but the phenotype is not aggravated further by combination with heterozygous moi1 allele.

      (Dubruille and Loppin, 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      1479/10
      (Deak et al., 1997)
      l(3)S147910
      (Dubruille and Loppin, 2015, Raffa et al., 2010)
      l(3)S147910S147910
      ver2
      (Cenci et al., 2015, Dubruille and Loppin, 2015, Raffa et al., 2010)
      verS147910
      (Zhang et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)