FB2026_02 , released June 18, 2026
Allele: Dmel\hbsUAS.cAa
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General Information
Symbol
Dmel\hbsUAS.cAa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Artero
FlyBase ID
FBal0130215
Feature type
allele
Associated gene
Dmel\hbs
Associated Insertion(s)
Carried in Construct
P{UAS-hbs.A}
Also Known As
UAS-hbs
Key Links
Transgenic product class
cDNA
(Artero et al., 2001)
wild_type
(Artero et al., 2001)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Artero et al., 2001)
wild_type
(Artero et al., 2001)
Mutagen
in vitro construct
(Artero et al., 2001)
Progenitor genotype
Carried in construct
P{UAS-hbs.A}
Cytology
Description

UASt sequences drive expression of a full length hbs cDNA.

(Artero et al., 2001)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
hbs
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of hbsUAS.cAa under the control of Scer\GAL4GMR.PF leads to a large increase in the percentage of R8 cells expressing Rh5 and a modest decrease in Rh3 expressing R7 cells.

      (Tan et al., 2020)

      When hbsScer\UAS.cAa is driven by Scer\GAL4twi.PB and Scer\GAL4Mef2.PR simultaneously, defects are seen in the somatic and visceral mesoderm. In the somatic mesoderm, a partial fusion block with free myoblasts scattered at several locations. Significant muscle loss is also seen. Founder cells are correctly specified in these embryos, but at later stages, aberrant morphologies are seen in the growing muscles.

      (Artero et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Scer\GAL4GMR.PF, hbsUAS.cAa has ommatidium phenotype, suppressible | partially by sev14

      (Tan et al., 2020)

      Scer\GAL4GMR.PF, hbsUAS.cAa has photoreceptor cell R8 phenotype, suppressible | partially by sev14

      (Tan et al., 2020)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The addition of hbsScer\UAS.cAa to Df(1)w67k30 embryos has no effect on the embryonic muscle phenotype seen in these embryos.

      (Artero et al., 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      hbsScer\UAS.cAa
      hbsUAS.cAa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Artero
      (Artero et al., 2001)
      Secondary FlyBase IDs
        References (3)