FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\Myd88EP2133
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General Information
Symbol
Dmel\Myd88EP2133
Species
D. melanogaster
Name
FlyBase ID
FBal0130899
Feature type
allele
Associated gene
Dmel\Myd88
Associated Insertion(s)
P{EP}Myd88EP2133
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Kambris et al., 2003, Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EP}Myd88EP2133
Cytology
Description

Insertion in the 5' untranslated region.

(Tauszig-Delamasure et al., 2002)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      VA1d olfactory receptor neuron axon targeting is normal in mutant flies.

      (Ward et al., 2015)

      Mutant flies that have been challenged with vesicular stomatitis virus show levels of viral replication that are not significantly different to that seen in wild-type controls.

      (Nakamoto et al., 2012)

      Homozygous flies show a reduced resistance to infection by the fungus B. bassiana and the Gram-positive bacterium Streptococcus faecalis compared to controls, but they show normal survival after infection by E. coli.

      (Tauszig-Delamasure et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      Myd88EP2133 is a non-suppressor of wing phenotype of Scer\GAL4dpp.PS, TolloUAS.cYa

      (Yagi et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      A Myd88EP2133 homozygous background does not suppress the bifurcated wing phenotype seen upon expression of TolloScer\UAS.cYa under the control of Scer\GAL4dpp.PS.

      (Yagi et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Precise excision of the insertion reverts the immune response phenotype.

      (Tauszig-Delamasure et al., 2002)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      Reported As
      Symbol Synonym
      DmMyD88EP(2)2133
      (Kambris et al., 2003)
      MyD88EP(2)2133
      (Diangelo et al., 2009)
      MyD88EP2133
      (Nakamoto et al., 2012)
      Myd88EP2133
      dMyD88EP2133
      (Ward et al., 2015)
      dMyd88<up>EP2133
      (Yagi et al., 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)