FlyBase Allele Report: Dmel\Dp1[EP2249]

General Information

Symbol

Dmel\Dp1^EP2249

Species

D. melanogaster

Name

FlyBase ID

FBal0131257

Feature type

allele

Associated gene

Dmel\Dp1

Associated Insertion(s)

P{EP}Dp1^EP2249

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

hypomorphic allele - genetic evidence

Mutagen

P-element activity

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Huertas et al., 2004)

Mutagen

P-element activity

(Gene Disruption Project members, 2001-, FlyBase, 1996-)

Progenitor genotype

Associated Insertion(s)

P{EP}Dp1^EP2249

Cytology

Description

P{EP} insertion in the second intron of Dp1.

(Huertas et al., 2004)

The P{EP}Dp1^EP2249 insertion maps within both Dp1 and imd (overlapping genes on opposite strands).

(FlyBase, 1996-)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:18,413,401..18,413,401 [+]

(Huertas et al., 2004, Gene Disruption Project members, 2001-, FlyBase, 1996-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female sterile | recessive

(Huertas et al., 2004)

non-suppressor of variegation, with In(1)w^m4

(Huertas et al., 2004)

partially lethal (with Df(2R)PC4)

(Huertas et al., 2004)

suppressor of variegation | dominant, with P{hsp26-pt-T}39C-41

(Huertas et al., 2004)

suppressor of variegation | dominant, with P{hsp26-pt-T}39C-42

(Huertas et al., 2004)

suppressor of variegation | dominant, with P{hsp26-pt-T}118E-25-5

(Huertas et al., 2004)

viable

(Huertas et al., 2004)

viable (with Dp1^15.1)

(Huertas et al., 2004)

Phenotype Manifest In

ovary

(Huertas et al., 2004)

Detailed Description

Statement

Reference

Homozygous females have underdeveloped ovaries and reduced fertility.

(Huertas et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

The site of the P{lacW}Dp1^SH2987 insertion is 752bp upstream of the site of the P{EP}Dp1^EP2422 insertion.

(Huertas et al., 2004)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Dp1^EP2249

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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