FlyBase Allele Report: Dmel\D1[EP473]

General Information

Symbol

Dmel\D1^EP473

Species

D. melanogaster

Name

FlyBase ID

FBal0131273

Feature type

allele

Associated gene

Dmel\D1

Associated Insertion(s)

P{EP}D1^EP473

Carried in Construct

Also Known As

EP473

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Cuvier et al., 2002, Pena-Rangel et al., 2002, Gene Disruption Project members, 2001-)

Progenitor genotype

Associated Insertion(s)

P{EP}D1^EP473

Cytology

Description

D1 protein and RNA are detectable in ovarian tissue of D1^EP473 flies.

(Weiler and Chatterjee, 2009)

P{EP} insertion in the 5' UTR of D1.

(Cuvier et al., 2002)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:9,240,251..9,240,251 [-]

(Weiler and Chatterjee, 2009, Sun et al., 2006, Cuvier et al., 2002, Pena-Rangel et al., 2002, Gene Disruption Project members, 2001-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

enhancer of variegation, with T(2;3)Sb^V

(Weiler and Chatterjee, 2009)

lethal | recessive

(Cuvier et al., 2002)

viable

(Weiler and Chatterjee, 2009)

viable (with D1^EY05004)

(Weiler and Chatterjee, 2009)

viable (with Df(3R)BSC24)

(Weiler and Chatterjee, 2009)

viable (with Df(3R)Exel6152)

(Weiler and Chatterjee, 2009)

Phenotype Manifest In

Detailed Description

Statement

Reference

D1^EP473 enhances variegation of Sb in T(2;3)Sb^V.

(Weiler and Chatterjee, 2009)

Homozygotes die at embryonic or early larval stages.

(Cuvier et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

D1^EP473, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Scer\GAL4^GMR.PF, lap^EP3060

(Sun et al., 2006)

D1^EP473, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Scer\GAL4^GMR.PF, kay^EP3084

(Sun et al., 2006)

Scer\GAL4^pnr-MD237/D1^EP473 is an enhancer of visible phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

Other

Statement

Reference

D1^EP473, Scer\GAL4^GMR.PF, cnc^EP3258 has visible phenotype

(Sun et al., 2006)

D1^EP473, EP3916^EP3916, Scer\GAL4^GMR.PF has visible phenotype

(Sun et al., 2006)

D1^EP473, EP893^EP893, Scer\GAL4^GMR.PF has visible phenotype

(Sun et al., 2006)

D1^EP473, EP3377^EP3377, Scer\GAL4^GMR.PF has visible phenotype

(Sun et al., 2006)

D1^EP473, Scer\GAL4^GMR.PF, XNP^EP635 has visible phenotype

(Sun et al., 2006)

Atx2^EP3145, D1^EP473, Scer\GAL4^GMR.PF has visible phenotype

(Sun et al., 2006)

D1^EP473, Scer\GAL4^GMR.PF, jigr1^EP3354 has visible phenotype

(Sun et al., 2006)

D1^EP473, Scer\GAL4^GMR.PF, jing^UAS.cSa has visible phenotype

(Sun et al., 2006)

D1^EP473, Scer\GAL4^GMR.PF, nuf^EP3339 has visible phenotype

(Sun et al., 2006)

D1^EP473, EP3303^EP3303, Scer\GAL4^GMR.PF has visible phenotype

(Sun et al., 2006)

Phenotype Manifest In

Enhancer of

Statement

Reference

D1^EP473, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, lap^EP3060

(Sun et al., 2006)

D1^EP473, Scer\GAL4^GMR.PF is an enhancer of ommatidium phenotype of Scer\GAL4^GMR.PF, lap^EP3060

(Sun et al., 2006)

D1^EP473, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, kay^EP3084

(Sun et al., 2006)

D1^EP473, Scer\GAL4^GMR.PF is an enhancer of ommatidium phenotype of Scer\GAL4^GMR.PF, kay^EP3084

(Sun et al., 2006)

Other

Statement

Reference

D1^EP473, EP3916^EP3916, Scer\GAL4^GMR.PF has ommatidium phenotype

(Sun et al., 2006)

D1^EP473, EP893^EP893, Scer\GAL4^GMR.PF has ommatidium phenotype

(Sun et al., 2006)

D1^EP473, EP3377^EP3377, Scer\GAL4^GMR.PF has ommatidium phenotype

(Sun et al., 2006)

D1^EP473, Scer\GAL4^GMR.PF, XNP^EP635 has eye phenotype

(Sun et al., 2006)

D1^EP473, Scer\GAL4^GMR.PF, XNP^EP635 has ommatidium phenotype

(Sun et al., 2006)

D1^EP473, Scer\GAL4^GMR.PF, jing^UAS.cSa has eye phenotype

(Sun et al., 2006)

Atx2^EP3145, D1^EP473, Scer\GAL4^GMR.PF has eye phenotype

(Sun et al., 2006)

Atx2^EP3145, D1^EP473, Scer\GAL4^GMR.PF has ommatidium phenotype

(Sun et al., 2006)

D1^EP473, Scer\GAL4^GMR.PF, jigr1^EP3354 has eye phenotype

(Sun et al., 2006)

D1^EP473, Scer\GAL4^GMR.PF, jigr1^EP3354 has ommatidium phenotype

(Sun et al., 2006)

D1^EP473, Scer\GAL4^GMR.PF, jing^UAS.cSa has ommatidium phenotype

(Sun et al., 2006)

D1^EP473, Scer\GAL4^GMR.PF, nuf^EP3339 has ommatidium phenotype

(Sun et al., 2006)

D1^EP473, EP3303^EP3303, Scer\GAL4^GMR.PF has ommatidium phenotype

(Sun et al., 2006)

D1^EP473, Scer\GAL4^GMR.PF, cnc^EP3258 has ommatidium phenotype

(Sun et al., 2006)

D1^EP473, Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+] has scutellum phenotype

(Pena-Rangel et al., 2002)

D1^EP473, Scer\GAL4^pnr-MD237, pnr^MD237/pnr[+] has macrochaeta | increased number phenotype

(Pena-Rangel et al., 2002)

D1^EP473, Scer\GAL4^pnr-MD237, pnr^MD237 has scutellum phenotype

(Pena-Rangel et al., 2002)

D1^EP473, Scer\GAL4^pnr-MD237, pnr^MD237 has macrochaeta | increased number phenotype

(Pena-Rangel et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Eye colour: D1^EP473/+ does not increase eye pigmentation of flies carrying w^BE28.1.2.3' in a w^- background in 7 out of 10 w^BE28.1.2.3' transgenic lines tested.

(Cuvier et al., 2002)

pnr^MD237/+ adults expressing D1^EP473 under the control of Scer\GAL4^pnr-MD237 have extra macrochaetae and a reduced scutellum.

(Pena-Rangel et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Separable from: An extraneous lethal mutation on the chromosome.

(Weiler and Chatterjee, 2009)

Selected as: a P{EP} insertion line that modifies the pnr^MD237/+ phenotype when expressed using Scer\GAL4^pnr-MD237.

(Pena-Rangel et al., 2002)

Comments

Complements: ird1^unspecified.

(Wu et al., 2007)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

D1^EP473

(Weiler and Chatterjee, 2009)

EP473

(Wu et al., 2007)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections