FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\CalrEP1084
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General Information
Symbol
Dmel\CalrEP1084
Species
D. melanogaster
Name
FlyBase ID
FBal0131292
Feature type
allele
Associated gene
Dmel\Calr
Associated Insertion(s)
P{EP}CalrEP1084
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Stoltzfus et al., 2003)
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EP}CalrEP1084
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      CrcEP1084/CrcEP834 and CrcEP1084/CrcEP3167 flies reproducibly exhibit a reduction in avoidance of the olfactory repellant 3-octanol compared to wild-type flies in an olfactory T-maze. Flies that are heteroallelic for CrcEP979/CrcEP1084 have little or no odour avoidance defects. CrcEP1084/CrcEP3167 flies also exhibit a reduction in avoidance of the olfactory repellants benzaldehyde and 4-methylcyclohexanol. Reduced avoidance of 4-methylcyclohexanol is most pronounced at low concentrations. However, CrcEP1084/CrcEP3167 flies are attracted to the olfactory attractants ethyl acetate and isoamyl acetate to the same extent as wild-type flies. The exploratory activity and climbing ability of CrcEP1084/CrcEP3167 mutant flies is not significantly different from wild type. Additionally, CrcEP1084/CrcEP3167 mutant flies have a normal electroantennogram amplitude in response to both 3-octanol and 4-methylcyclohexanol. Areas of the brain important for locomotion and olfaction in CrcEP1084/CrcEP3167 mutants have no obvious morphological differences from the wild type.

      (Stoltzfus et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Separable from: a secondary uncharacterised recessive lethal mutation on the chromosome.

      (Stoltzfus et al., 2003)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CalrEP1084
      Crc10
      (Stoltzfus et al., 2003)
      CrcEP1084
      Name Synonyms
      Secondary FlyBase IDs
        References (2)