FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Sp7KG02818
Open Close
General Information
Symbol
Dmel\Sp7KG02818
Species
D. melanogaster
Name
FlyBase ID
FBal0131522
Feature type
allele
Associated gene
Dmel\Sp7
Associated Insertion(s)
P{SUPor-P}Sp7KG02818
Carried in Construct
Also Known As
CG3066KG02818
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{SUPor-P}Sp7KG02818
Cytology
Description

Insertion in the second exon.

(Leclerc et al., 2006)
Allele components
Component
Use(s)
Inserted element
P{SUPor-P}
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies expressing Sp7KG02818 under the control of Scer\GAL4unspecified do not exhibit any significant difference in survival rate of flies either untreated or treated with Leishmania amastigotes, as compared to wild type.

      (Okuda et al., 2016)

      Sp7KG02818/Sp7KG02818 adult flies show significant decreases in survival to bacterial infection with either Providencia rettgeri (severe) or Enterococcus faecalis (moderate), as compared to controls.

      (Chambers et al., 2014)

      Mutant flies show the same survival as wild-type controls after natural infection with B. bassiana or after challenge with a needle contaminated with either A. tumefaciens, E. faecalis, E. coli or S. aureus.

      (Leclerc et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Separable from: a second site mutation that results in strong susceptibility to B. bassiana infection.

      (Leclerc et al., 2006)
      Comments
      Comments

      Precise excision of the insertion reverts the mutant phenotype of lack of phenoloxidase cleavage after immune challenge.

      (Leclerc et al., 2006)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CG3066KG02818
      (Okuda et al., 2016, Leclerc et al., 2006)
      Sp7KG02818
      sp7KG0180
      (Chambers et al., 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)