FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\witG15
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General Information
Symbol
Dmel\witG15
Species
D. melanogaster
Name
FlyBase ID
FBal0133969
Feature type
allele
Associated gene
Dmel\wit
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        witG15 mutant dorsal cluster neuron clones appear normal.

        (Zheng et al., 2006)

        Mutant clones fail to exhibit any visible defects in mushroom body remodelling.

        (Zheng et al., 2003)

        Germline clones produce animals that die during the pharate adult stage.

        (Marques et al., 2002)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        NOT Enhancer of
        Statement
        Reference

        put62/witG15 is a non-enhancer of partially lethal - majority die phenotype of Neto109

        (Sulkowski et al., 2014)
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Larvae that are heterozygous for both put62 and witG15 have a similar number of boutons to wild type.

        Larvae that are heterozygous for Neto36, witG15 and put62 have smaller NMJs with 25% fewer synaptic boutons.

        (Sulkowski et al., 2014)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        WitG15
        (Marmion et al., 2013)
        witG15
        (Wang et al., 2019, Sulkowski et al., 2014, Smith et al., 2012)
        Name Synonyms
        Secondary FlyBase IDs
          References (7)