FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\EcRKG04522
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General Information
Symbol
Dmel\EcRKG04522
Species
D. melanogaster
Name
FlyBase ID
FBal0134267
Feature type
allele
Associated gene
Dmel\EcR
Associated Insertion(s)
P{SUPor-P}EcRKG04522
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{SUPor-P}EcRKG04522
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{SUPor-P}
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  acute myeloid leukemia
      modeled by Hsap\RUNX1::Hsap\RUNX1T1UAS.cSa
      (Sinenko et al., 2010)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      One copy of EcRKG04522 has no effect on hemocyte proliferation in third instar larvae.

      (Sinenko et al., 2010)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      EcR[+]/EcRKG04522 is a non-suppressor of increased cell number | third instar larval stage phenotype of hopTum

      (Sinenko et al., 2010)
      Phenotype Manifest In
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      EcR[+]/EcRKG04522 is a non-suppressor of embryonic/larval hemocyte | third instar larval stage phenotype of hopTum

      (Sinenko et al., 2010)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      One copy of EcRKG04522 is unable to suppress the hemocyte overproliferation seen in hopTum mutant third instar larvae.

      (Sinenko et al., 2010)
      Xenogenetic Interactions
      Statement
      Reference

      One copy of EcRKG04522 strongly suppresses the hemocyte overproliferation seen in third instar larvae when Hsap\RUNX1::Hsap\RUNX1T1Scer\UAS.cSa is expressed under the control of Scer\GAL4Hml.Δ.

      (Sinenko et al., 2010)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      EcR KG04522
      (Sinenko et al., 2010)
      EcRKG04522
      (Sinenko et al., 2010)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)