FlyBase Allele Report: Dmel\l(3)L4092[EP3690]

General Information

Symbol

Dmel\l(3)L4092^EP3690

Species

D. melanogaster

Name

FlyBase ID

FBal0135678

Feature type

allele

Associated gene

l(3)L4092

Associated Insertion(s)

P{EP}l(3)L4092^EP3690

Carried in Construct

Also Known As

EP(3)3690

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Pena-Rangel et al., 2002)

Progenitor genotype

Associated Insertion(s)

P{EP}l(3)L4092^EP3690

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:9,341,838..9,341,838 [+]

(Schulz et al., 2004, Pena-Rangel et al., 2002)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

germline cell | male, with Scer\GAL4^{VP16.nanos.UTR}

(Schulz et al., 2004)

Detailed Description

Statement

Reference

Expression of l(3)L4092^EP3690 under the control of Scer\GAL4^{nos.UTR.T:Hsim\VP16} (the animals are initially raised at 18^oC and are then shifted to 29^oC after 7 days) results in a reduced number of early germ cells (stem cells, gonialblasts and spermatogonia) in the testis.

(Schulz et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

Scer\GAL4^pnr-MD237/l(3)L4092^EP3690 is an enhancer of visible phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

Phenotype Manifest In

Other

Statement

Reference

Scer\GAL4^pnr-MD237, l(3)L4092^EP3690, pnr^MD237/pnr[+] has scutellum phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, l(3)L4092^EP3690, pnr^MD237/pnr[+] has adult thorax phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, l(3)L4092^EP3690, pnr^MD237 has scutellum phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, l(3)L4092^EP3690, pnr^MD237 has adult thorax phenotype

(Pena-Rangel et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

pnr^MD237/+ adults expressing l(3)L4092^EP3690 under the control of Scer\GAL4^pnr-MD237 have a deformed thorax and scutellum.

(Pena-Rangel et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a P{EP} insertion line that modifies the pnr^MD237/+ phenotype when expressed using Scer\GAL4^pnr-MD237.

(Pena-Rangel et al., 2002)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

l(3)L4092^EP3690

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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