FB2026_02 , released June 18, 2026
Allele: Dmel\WASpΔCA.UAS
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General Information
Symbol
Dmel\WASpΔCA.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0135765
Feature type
allele
Associated gene
Dmel\WASp
Associated Insertion(s)
Carried in Construct
P{UAS-WASp.ΔCA}
Key Links
Transgenic product class
inframe_deletion
(Tal et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Tal et al., 2002)
Mutagen
in vitro construct
(Tal et al., 2002)
Progenitor genotype
WASpUAS.cBa
(Tal et al., 2002)
Carried in construct
P{UAS-WASp.ΔCA}
Cytology
Description

The C-terminal 30 residues have been deleted.

(Tal et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
WASp
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of WASpΔCA.Scer\UAS in the mesoderm and muscle under the control of Scer\GAL4twi.PB results in a strong myoblast fusion phenotype.

      Expression of WASpΔCA.Scer\UAS under the control of Scer\GAL4kirre.PR has no obvious effects on myogenesis.

      (Massarwa et al., 2007)

      Expression of WASpΔCA.Scer\UAS in the mesoderm under the control of Scer\GAL4twi.PG results in myoblast fusion defects. Fusion rounds appear to stop after precursor formation.

      Expression of WASpΔCA.Scer\UAS in founder cells under the control of Scer\GAL4kirre-rP298 does not disrupt myoblast fusion.

      (Schafer et al., 2007)

      Expression of WASpΔCA.Scer\UAS under the control of Scer\GAL4en-e16E in the posterior compartment of the third larval instar wing disc has no effect on F-actin or G-actin distribution.

      Expression of WASpΔCA.Scer\UAS under the control of Scer\GAL4sca-537.4 results in a loss of thoracic bristles.

      (Bogdan et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of WASpΔCA.Scer\UAS suppresses the ectopic F-actin formation seen when AbiScer\UAS.T:Myr1 is expressed under the control of Scer\GAL4en-e16E in the posterior compartment of the third larval instar wing disc.

      (Bogdan et al., 2005)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Scer\GAL4arm.PS/WASpΔCA.UAS fails to rescue Df(3R)3450/WASp1

      (Tal et al., 2002)
      Comments

      The addition of WASpΔCA.Scer\UAS driven by Scer\GAL4arm.PS, fails to rescue the bristle phenotype seen in WASp1/Df(3R)3450 adults.

      (Tal et al., 2002)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      WASpΔCA.Scer\UAS
      WASpΔCA.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (4)