FlyBase Allele Report: Dmel\γCOP[S057302]

General Information

Symbol

Dmel\γCOP^S057302

Species

D. melanogaster

Name

FlyBase ID

FBal0137677

Feature type

allele

Associated gene

Dmel\γCOP

Associated Insertion(s)

P{lacW}γCOP^S057302

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

P-element activity

(Salzberg et al., 1997)

Delta2-3 transposase

(Deak et al., 1997)

Progenitor genotype

Associated Insertion(s)

P{lacW}γCOP^S057302

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:31,572,276..31,572,500

(Jayaram et al., 2008, Ecovoiu et al., 2005, Ecovoiu et al., 2002)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

AJ492220

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal (with γCOP^1b)

(Ecovoiu et al., 2005)

lethal (with γCOP^5a)

(Ecovoiu et al., 2005)

lethal (with γCOP^6a)

(Ecovoiu et al., 2005)

lethal (with γCOP^7a)

(Ecovoiu et al., 2005)

lethal (with γCOP^8a)

(Ecovoiu et al., 2005)

lethal (with γCOP^9a)

(Ecovoiu et al., 2005)

lethal (with γCOP^10a)

(Ecovoiu et al., 2005)

lethal (with γCOP^11a)

(Ecovoiu et al., 2005)

lethal (with γCOP^14a)

(Ecovoiu et al., 2005)

lethal (with γCOP^15a)

(Ecovoiu et al., 2005)

lethal (with γCOP^16a)

(Ecovoiu et al., 2005)

lethal (with γCOP^16b)

(Ecovoiu et al., 2005)

lethal (with γCOP^17b)

(Ecovoiu et al., 2005)

lethal (with γCOP^20b)

(Ecovoiu et al., 2005)

lethal (with γCOP^21b)

(Ecovoiu et al., 2005)

lethal | recessive

(Ecovoiu et al., 2002, Deak et al., 1997)

lethal - all die during embryonic stage | recessive

(Salzberg et al., 1997)

some die during embryonic stage | recessive

(Salzberg et al., 1997)

Phenotype Manifest In

embryonic/larval tracheal dorsal trunk

(Jayaram et al., 2008)

presumptive embryonic/larval nervous system

(Salzberg et al., 1997)

Detailed Description

Statement

Reference

At early stage 16, the dorsal trunk tubes of mutant embryos are narrower compared to those of controls.

(Jayaram et al., 2008)

Early lethal.

(Deak et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

Rescued by

γCOP^Δ114/γCOP^S057302 is rescued by Scer\GAL4^btl.PS/γCOP^UAS.cJa

(Jayaram et al., 2008)

γCOP^Δ114/γCOP^S057302 is rescued by γCOP^αTub84B.PJ

(Jayaram et al., 2008)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

4544

y¹ w^67c23; P{lacW}γCOP^S057302/TM3, Sb¹ Ser¹

Notes on Origin

Discoverer

Comments

Precise excision of the P{lacW} insertion can revert the lethal phenotype, indicating that the P{lacW}γCop^S057302 insertion within the γCop gene is responsible for the homozygous lethality of the "l(3)S057302" chromosome.

(Ecovoiu et al., 2002)

Reversion analysis demonstrates the insertion may not be responsible for the lethal phenotype.

(Salzberg et al., 1997)

External Crossreferences and Linkouts ( 1 )

Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AJ492220

Synonyms and Secondary IDs (9)

Reported As

Symbol Synonym

0573/02

(Deak et al., 1997)

573.02

(Salzberg et al., 1997)

l(3)S057302^S057302

(Johannes and Preiss, 2002)

l(3)S057302b^S057302b

l(3)s057302

(Jayaram et al., 2008)

γCOP^P1

(Jayaram et al., 2008)

γCOP^S057302

(Chifiriuc et al., 2022)

γCop^S057302

(Ecovoiu et al., 2007)

γCop^S057302a

Name Synonyms

Secondary FlyBase IDs

FBal0105011

References (8)

Report Sections

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