FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\rgγ7
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General Information
Symbol
Dmel\rgγ7
Species
D. melanogaster
Name
FlyBase ID
FBal0138150
Feature type
allele
Associated gene
Dmel\rg
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Shamloula et al., 2002)
Mutagen
gamma ray
(Shamloula et al., 2002)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      rgγ7 mutants display abnormal type I bouton morphology: changes in shape, fusion of boutons. Size of type I boutons remains unchanged but their number is significantly decreased.

      rgγ7 mutants show altered synaptic transmission at larval neuromuscular junctions with abnormally large excitatory junctional potentials.

      rgγ7 mutants show decreased frequency of peristaltic contractions, decreased speed of movement and are more likely to be in a curled position.

      rgγ7 mutants show increased habituation of the giant fiber circuit in adults.

      (Wise et al., 2015)

      Moderate rough eye phenotype.

      (Shamloula et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      rg1

      (Shamloula et al., 2002)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      rgγ7
      (Wise et al., 2015)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)