FlyBase Allele Report: Dmel\bab2[Fpa1]

General Information

Symbol

Dmel\bab2^Fpa1

Species

D. melanogaster

Name

FlyBase ID

FBal0138339

Feature type

allele

Associated gene

Dmel\bab2

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

gamma ray

Nature of the Allele

Allele class

Mutagen

gamma ray

(Couderc et al., 2002)

Progenitor genotype

Caused by aberration

Df(3L)Fpa1

Cytology

Description

Deficiency breakpoint in the second intron of bab2.

(Couderc et al., 2002)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Df(3L)Fpa2, bab2^Fpa1 has visible | recessive phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has abnormal body color phenotype

(Couderc et al., 2002)

Df(3L)Fpa1, bab2^Fpa1 has female sterile | recessive phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has visible phenotype

(Couderc et al., 2002)

Phenotype Manifest In

Other

Statement

Reference

Df(3L)Fpa2, bab2^Fpa1 has tarsal segment 2 phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has tarsal segment 3 phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has abdominal tergite 6 | anterior phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has abdominal tergite 6 | female phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has abdominal tergite 7 | anterior phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has abdominal tergite 7 | female & macrochaeta | ectopic phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has abdominal tergite 7 | female phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has abdominal tergite 8 | anterior phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has chaeta & abdominal sternite 6 | female phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has chaeta & abdominal sternite 7 | female phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has hypogynial tooth phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has leg phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has metathoracic tarsal bristle phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has ovary phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has prothoracic tarsal bristle phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has tarsal segment 4 phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has pretarsus phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has abdominal sternite 6 | female phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has abdominal sternite 7 | female phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has abdominal tergite 2 | anterior phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has abdominal tergite 3 | anterior phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has abdominal tergite 4 | anterior phenotype

(Couderc et al., 2002)

Df(3L)Fpa2, bab2^Fpa1 has abdominal tergite 5 | anterior phenotype

(Couderc et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Df(3L)Fpa1/Df(3L)Fpa2 females have a very strong mutant ovary phenotype; the ovaries are very small and no developing follicles are seen. Df(3L)Fpa1/Df(3L)Fpa2 adults have a very strong mutant leg phenotype; tarsal segments TS5 to TS2 are often fused into a single segment. The bristle pattern of TS2-TS4 is transformed. Df(3L)Fpa1/Df(3L)Fpa2 adults have pigmentation defects in the tergites in both sexes; a thorough dark pigmentation is found in A3-A8/A9 and also with low penetrance in A2. The ectopic dark pigmentation in A2 and A3 is patchy and usually restricted to the anterior margin. In Df(3L)Fpa1/Df(3L)Fpa2 females, the two tergite plates of A7 are fused and enlarged and have more large bristles than normal. The A6 tergite is also enlarged. The two rows of thorn bristles are replaced by a different type of bristle, which are longer and twisted. The shape, pigmentation pattern and bristle pattern of the A6 and A7 sternites in Df(3L)Fpa1/Df(3L)Fpa2 females are different from wild-type females and more show similarities to the A6 sternite in wild-type males.

(Couderc et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

bab2^Fpa1

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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