FB2026_02 , released June 18, 2026
Allele: Dmel\Jra::kayFJF.hs.sev
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General Information
Symbol
Dmel\Jra::kayFJF.hs.sev
Species
D. melanogaster
Name
FlyBase ID
FBal0138477
Feature type
allele
Associated gene
Jra::kay
Associated Insertion(s)
Carried in Construct
P{hs.sev-Jra::kay.FJF}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Ciapponi and Bohmann, 2002)
Progenitor genotype
Carried in construct
P{hs.sev-Jra::kay.FJF}
Cytology
Description

The sev enhancer and a heat shock promoter drive expression of kay, in which the leucine zipper domain has been replaced with the leucine zipper domain of Jra.

(Ciapponi and Bohmann, 2002)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
sev
Encoded product / tool
Jra::kay
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Jra::kayFJF.hs.sev is a suppressor of lethal phenotype of kay1/kay2

      (Ciapponi and Bohmann, 2002)
      NOT Suppressor of
      Statement
      Reference

      Jra::kayFJF.hs.sev is a non-suppressor of lethal | recessive phenotype of JraIA109

      (Ciapponi and Bohmann, 2002)
      Phenotype Manifest In
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      Jra::kayFJF.hs.sev is a non-suppressor of embryonic dorsal epidermis phenotype of JraIA109

      (Ciapponi and Bohmann, 2002)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The dorsal open phenotype of JraIA109 homozygous embryos is not rescued by Jra::kayFJF.hs.sev. The dorsal open phenotype of kay1/kay2 and kay1 homozygous embryos is at least partially rescued by Jra::kayFJF.hs.sev. kay1/kay2 adults rescued by the expression of Jra::kayFJF.hs.sev have a marked cleft along the dorsal midline of the thorax.

      (Ciapponi and Bohmann, 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Jra::kayFJF.hs.sev
      Name Synonyms
      Secondary FlyBase IDs
        References (1)