FlyBase Allele Report: Dmel\Gp150[P8]

General Information

Symbol

Dmel\Gp150^P8

Species

D. melanogaster

Name

FlyBase ID

FBal0138495

Feature type

allele

Associated gene

Dmel\Gp150

Associated Insertion(s)

P{lacW}Gp150^P8

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Fetchko et al., 2002)

Progenitor genotype

P{lacW}px^k08134

(Fetchko et al., 2002)

Associated Insertion(s)

P{lacW}Gp150^P8

Cytology

Description

P{lacW} insertion maps to the second intron of the Gp150 transcription unit, 53bp downstream of the second exon.

(Fetchko et al., 2002)

P-element insertion in the second intron.

(Melnattur et al., 2002)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:22,318,007..22,318,014 [+]

(Fetchko et al., 2002, Melnattur et al., 2002)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

ommatidium (with Gp150^k11120b)

(Fetchko et al., 2002)

Detailed Description

Statement

Reference

19.2% of ommatidia in Gp150^P8/Gp150^k11120b animals are mutant.

(Fetchko et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

Gp150^k11120b/Gp150^P8 has ommatidium phenotype, enhanceable by Delta^6B

(Fetchko et al., 2002)

Gp150^k11120b/Gp150^P8 has ommatidium phenotype, enhanceable by Delta^9P

(Fetchko et al., 2002)

Gp150^k11120b/Gp150^P8 has ommatidium phenotype, enhanceable by N^55e11

(Fetchko et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

The addition of N^55e11/+ to Gp150^P8/Gp150^k11120b animals increases the proportion of mutant ommatidia from 19.2% to 42.3%. The addition of Dl^9P/+ to Gp150^P8/Gp150^k11120b animals increases the proportion of mutant ommatidia from 19.2% to 67.6%. The addition of Dl^9P/+ to Gp150^P8/Gp150^k11120b animals increases the proportion of mutant ommatidia from 19.2% to 44.6%.

(Fetchko et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

Phenotype is revertable on excision of the P-element.

(Fetchko et al., 2002)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Gp150^P8

gp150^P8

(Melnattur et al., 2002)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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