FlyBase Allele Report: Dmel\Axn[unspecified]

General Information

Symbol

Dmel\Axn^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0138578

Feature type

allele

Associated gene

Dmel\Axn

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

(FlyBase Curators, 2025-)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible | somatic clone

(Olson et al., 2011, Belenkaya et al., 2002)

Phenotype Manifest In

embryonic/first instar larval cuticle

(Belenkaya et al., 2002)

eye | somatic clone

(Olson et al., 2011)

eye disc | somatic clone

(Olson et al., 2011)

photoreceptor neuron | somatic clone

(Parker et al., 2002)

wing & chaeta | ectopic | somatic clone

(Belenkaya et al., 2002)

wing | somatic clone

(Belenkaya et al., 2002)

Detailed Description

Statement

Reference

Homozygous clones in the eye result in patches of naked cuticle lacking photoreceptors.

In homozygous clones in the eye disc, cells remain apically constricted several rows posterior to the morphogenetic furrow, in contrast to wild type.

(Olson et al., 2011)

Stage 5-8 embryos derived from homozygous germline clones show a significant delay of initial glycogen decomposition.

(Yamazaki and Yanagawa, 2003)

Embryos lacking both maternal and zygotic Axn function have a naked cuticle phenotype. Homozygous clones in the wing produce numerous ectopic bristles.

(Belenkaya et al., 2002)

Axn^unspecified clones in the eye, show photoreceptor development.

(Parker et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Axn^unspecified, pygo^unspecified has lethal | germline clone phenotype

(Parker et al., 2002)

Phenotype Manifest In

Suppressed by

Statement

Reference

Axn^unspecified has photoreceptor neuron | somatic clone phenotype, suppressible by pygo¹⁰

(Parker et al., 2002)

NOT Enhancer of

Statement

Reference

Axn^unspecified is a non-enhancer of imaginal disc phenotype of pygo¹⁰

(Parker et al., 2002)

NOT Suppressor of

Statement

Reference

Axn^unspecified is a non-suppressor of imaginal disc phenotype of pygo¹⁰

(Parker et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

Axn^unspecified pygo^F15 double null embryos have a "lawn of denticles" phenotype resembling the phenotype of pygo^F15 single mutant embryos. Axn^unspecified pygo^F15 double mutant clones in the wing result in wing notching and ectopic wing margin bristles, resembling the phenotype of pygo^F15 single mutant embryos.

(Belenkaya et al., 2002)

The addition of pygo¹⁰ completely suppresses the photoreceptor cell phenotype seen in Axn^unspecified mutants. Axn^unspecified pygo^unspecified double mutant germ-line clones only produces a few eggs that are not fertilised.

(Parker et al., 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Axn^unspecified

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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