FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mysunspecified
Open Close
General Information
Symbol
Dmel\mysunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0141029
Feature type
allele
Associated gene
Dmel\mys
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        The amnioserosa and lateral epidermis rip themselves apart and the embryos fail to complete dorsal closure.

        (Hutson et al., 2003)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhancer of
        Statement
        Reference

        mys[+]/mysunspecified is an enhancer of abnormal neuroanatomy | embryonic stage phenotype of Scer\GAL4P52, Sema1aUAS.cYa, Sema1ak13702

        (Cho et al., 2012)

        mys[+]/mysunspecified is an enhancer of visible | heat sensitive phenotype of Scer\GAL4337Y, ifLOF.m8.UAS

        (Baker et al., 2002)
        Suppressor of
        Statement
        Reference

        mysunspecified is a suppressor | partially | somatic clone of neoplasia | somatic clone | adult stage phenotype of NNIG.3936R, Scer\GAL4unspecified

        (Lin et al., 2013)

        mys[+]/mysunspecified is a suppressor of visible | heat sensitive phenotype of Scer\GAL4337Y, ifGOF.m8.UAS

        (Baker et al., 2002)
        Other
        Statement
        Reference

        Scer\GAL4337Y, ifLOF.m8.UAS, mys[+]/mysunspecified has lethal | heat sensitive phenotype

        (Baker et al., 2002)

        Scer\GAL4337Y, ifLOF.m8.UAS, mysunspecified has lethal | heat sensitive phenotype

        (Baker et al., 2002)
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        mys[+]/mysunspecified is an enhancer of larval posterior commissure | embryonic stage phenotype of Scer\GAL4P52, Sema1aUAS.cYa, Sema1ak13702

        (Cho et al., 2012)

        mys[+]/mysunspecified is an enhancer of wing | heat sensitive phenotype of Scer\GAL4337Y, ifLOF.m8.UAS

        (Baker et al., 2002)
        Suppressor of
        Statement
        Reference

        mysunspecified is a suppressor | partially | somatic clone of adult posterior midgut epithelium | somatic clone phenotype of NNIG.3936R, Scer\GAL4unspecified

        (Lin et al., 2013)

        mys[+]/mysunspecified is a suppressor of wing | heat sensitive phenotype of Scer\GAL4337Y, ifGOF.m8.UAS

        (Baker et al., 2002)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The commissural axon phenotype (failure to cross the midline) seen in embryos expressing Sema-1aScer\UAS.cYa under the control of Scer\GAL4P52 in a Sema-1ak13702 null background is significantly enhanced if the embryos are also heterozygous for mysunspecified.

        (Cho et al., 2012)

        S48-5/mysunspecified mutants show 4.44%+-2.59 misrotated ommatidia compared to 9.55%+-1.43 seen in S48-5 mutants alone.

        (Gaengel and Mlodzik, 2003)

        The wing blistering phenotype caused by expression of ifLOF.m8.Scer\UAS under the control of Scer\GAL4337Y is strongly enhanced by mysunspecified/+. The wing blistering phenotype caused by expression of ifGOF.m8.Scer\UAS under the control of Scer\GAL4337Y is completely suppressed by mysunspecified/+.

        (Baker et al., 2002)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        mysunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (6)