FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\elBd47
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General Information
Symbol
Dmel\elBd47
Species
D. melanogaster
Name
FlyBase ID
FBal0141141
Feature type
allele
Associated gene
Dmel\elB
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

amorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - genetic evidence

(Dorfman et al., 2002)
Mutagen
Delta2-3 transposase
(Dorfman et al., 2002)
Progenitor genotype
elBEP2039
(Dorfman et al., 2002)
Cytology
Description

Imprecise excision, removing the P{EP}elBEP2039 element. All sequences between the P{EP}elBEP2039 insertion site and elB are intact. There has been a deletion of genomic sequences in the region upstream of the P{EP}elBEP2039 insertion site. In addition, sequences corresponding to the opus element are detected upstream of the P{EP}elBEP2039 insertion site in elBd47, suggesting that an inversion coupled to a deletion of sequences upstream of the P{EP}elBEP2039 insertion site may have occurred.

(Dorfman et al., 2002)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous embryos show defects in tracheal development; there is no migration of the lateral trunk anterior branch and the ganglionic branches are shorter than normal. The cells which fail to migrate into the lateral trunk remain in the transverse connective. The number of cells that form the dorsal trunk and visceral branch is normal. Dorsal branch migration is impaired and failure of dorsal branch fusion is seen at stage 16. The number of cells in the dorsal branch is sometimes reduced. In some segments, the dorsal branch cells migrate abnormally and fusion between laterally adjacent dorsal branches is seen.

      (Dorfman et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescued by

      elBd47 is partially rescued by Scer\GAL4btl.PS/elBUAS.cDa

      (Dorfman et al., 2002)
      Comments

      Expression of elBScer\UAS.cDa under the control of Scer\GAL4btl.PS completely rescues migration of the lateral trunk anterior branch in elBd47 embryos, and partially rescues dorsal branch migration.

      (Dorfman et al., 2002)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      elBd47
      elBΔ47
      (Dorfman et al., 2002)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)