FB2026_02 , released June 18, 2026
Allele: Dmel\EphrinUAS.cBa
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General Information
Symbol
Dmel\EphrinUAS.cBa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Bossing
FlyBase ID
FBal0141753
Feature type
allele
Associated gene
Dmel\Ephrin
Associated Insertion(s)
Carried in Construct
P{UAS-Ephrin.B}
Key Links
Transgenic product class
wild_type
(Bossing and Brand, 2002)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Bossing and Brand, 2002)
Mutagen
in vitro construct
(Bossing and Brand, 2002)
Progenitor genotype
Carried in construct
P{UAS-Ephrin.B}
Cytology
Description

UASt regulatory sequences drive expression of full length Ephrin.

(Bossing and Brand, 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Ephrin
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of EphrinScer\UAS.cBa under the control of Scer\GAL4sim.PS results in fusion, severe thinning of loss of commissures without affecting midline glial cell differentiation. The contralateral axons are stalled at the midline. The extension of the ipsilateral axons immediately adjacent to the midline is unaffected. Expression of EphrinScer\UAS.cBa under the control of Scer\GAL4MZ1580 results in breaks in the connectives.

      (Bossing and Brand, 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of EphrinScer\UAS.cBa under the control of Scer\GAL4GH146 partially suppresses the targeting defects seen in homozygous meigo1 DL1 projection neuron clones.

      (Sekine et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in plasmid "UAS-Dephrin" and injected into embryos. Carried in plasmid "UAS-Dephrin" and transfected into S2 cells.

      (Bossing and Brand, 2002)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      EphrinScer\UAS.cBa
      EphrinUAS.cBa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Bossing
      (Bossing and Brand, 2002)
      Secondary FlyBase IDs
        References (2)