FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\roblMB
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General Information
Symbol
Dmel\roblMB
Species
D. melanogaster
Name
FlyBase ID
FBal0143259
Feature type
allele
Associated gene
Dmel\robl
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Reuter et al., 2003)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous roblMB mutant neurons in the third instar larva display abnormal dendritic arborization.

      (Satoh et al., 2008)

      Homozygous mushroom body neuroblast clones generated in newly hatched larvae and examined in the wandering third instar or single cell mushroom body neuron clones show a "spotty axon" phenotype; the mutant cells have periodic swellings along their axons or near the axon terminals. Homozygous mushroom body neuroblast clones examined in adults are mostly composed of γ neurons. Mutant mushroom body neuroblast clones generated in newly hatched larvae and examined in the wandering third instar have a reduced cell number compared to control clones.

      (Reuter et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      roblB

      (Reuter et al., 2003)

      roblZ

      (Reuter et al., 2003)
      Rescued by

      roblMB is rescued by Scer\GAL4elav.PU/roblUAS.Tag:HA

      (Copf, 2014)

      roblMB is rescued by Scer\GAL4elav.PU/roblSA.UAS.Tag:HA

      (Copf, 2014)
      Comments

      Expression of roblScer\UAS.T:Ivir\HA1 under the control of Scer\GAL4elav.PU rescues the arborization defects seen in the dendrites of roblMB mutant class IV dendritic arborization neurons.

      Expression of roblSA.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4elav.PU rescues the arborization defects seen in the dendrites of roblMB mutant class IV dendritic arborization neurons.

      (Copf, 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Separable from: a second lethal mutation on the chromosome (at 46E1--46F2).

      (Reuter et al., 2003)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      7A11
      (Reuter et al., 2003)
      robl(MB)
      (Copf, 2014)
      roblMB
      (Copf, 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)