FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\SmD1SH003
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General Information
Symbol
Dmel\SmD1SH003
Species
D. melanogaster
Name
FlyBase ID
FBal0143412
Feature type
allele
Associated gene
Dmel\SmD1
Associated Insertion(s)
P{lacW}SmD1SH003
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Oh et al., 2003)
Progenitor genotype
Associated Insertion(s)
P{lacW}SmD1SH003
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Most homozygotes die as larvae, with a few surviving for up to 2 weeks as small larvae.

      (Gonsalvez et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescued by

      SmD1SH003 is partially rescued by SmD1UASp.Venus/Scer\GAL4Tub.PU

      (Gonsalvez et al., 2008)

      SmD1SH003 is partially rescued by SmD1RK.UASp.Venus/Scer\GAL4Tub.PU

      (Gonsalvez et al., 2008)
      Not rescued by

      SmD1SH003 is not rescued by SmD1ΔRG.UASp.Venus/Scer\GAL4Tub.PU

      (Gonsalvez et al., 2008)
      Comments

      The lethality of SmD1SH003 animals is partially rescued by expression of either SmD1RK.Scer\UAS.P\T.T:Avic\GFP-YFP.Venus or SmD1RK.Scer\UAS.P\T.T:Avic\GFP-YFP.Venus under the control of Scer\GAL4tub.

      The lethality of SmD1SH003 animals is not rescued by expression of SmD1ΔRG.Scer\UAS.P\T.T:Avic\GFP-YFP.Venus under the control of Scer\GAL4tub, although the lethal phase is significantly delayed in these animals.

      (Gonsalvez et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      SmD1SH003
      (Garcia et al., 2024)
      l(3)SH003SH003
      snRNP69DP{lacW}l(3)<up>SH003</up>
      (Gonsalvez et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)