FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\gcm+t5.6
Open Close
General Information
Symbol
Dmel\gcm+t5.6
Species
D. melanogaster
Name
FlyBase ID
FBal0144280
Feature type
allele
Associated gene
Dmel\gcm
Associated Insertion(s)
Carried in Construct
P{2kb-glide}
Key Links
Transgenic product class
genomic_DNA
(Ragone et al., 2003)
wild_type
(Ragone et al., 2003)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Ragone et al., 2003)
wild_type
(Ragone et al., 2003)
Mutagen
in vitro construct
(Ragone et al., 2003)
Progenitor genotype
Carried in construct
P{2kb-glide}
Cytology
Description

Consists of 5.6kb HindIII-SalI fragment of genomic sequences including 2kb of upstream, and 1.7kb of downstream sequences.

(Ragone et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
gcm
gcm_2kb-glide
Encoded product / tool
gcm
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      gcm+t5.6 is a non-suppressor of larval lateral VNC glial cell phenotype of hkb2

      (De Iaco et al., 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The gcm+t5.6 transgene fails to rescue the absent glial phenotype of hkb2 mutants.

      (De Iaco et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      gcm+t5.6 rescues gcm26

      (De Iaco et al., 2006)

      gcm+t5.6 rescues gcmN7-4

      (Ragone et al., 2003)
      Comments

      The addition of gcm+t5.6 to gcmN7-4 animals leads to the rescue of subperineural glia (SPG), and peripheral glia (PG). This rescue is does dependent. Defects in the CNS and in the PNS are also partially rescued.

      (Ragone et al., 2003)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      gcm+t5.6
      Name Synonyms
      Secondary FlyBase IDs
        References (4)