FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Khc8.70
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General Information
Symbol
Dmel\Khc8.70
Species
D. melanogaster
Name
FlyBase ID
FBal0144776
Feature type
allele
Associated gene
Dmel\Khc
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Januschke et al., 2002)
Mutagen
ethyl methanesulfonate
(Januschke et al., 2002)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      oocyte & nucleus | germ-line clone

      (Januschke et al., 2002)
      Detailed Description
      Statement
      Reference

      Khc8.70 germ line clone oocytes have mis-positioned nuclei: the nucleus migrates correctly to the anterior during stage 8, but in about 50% of stage 9 oocytes it does not maintain its anterior position. After anterior detachment, the nucleus maintains a tight association with the lateral cortex.

      (Januschke et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      Khc27

      (Januschke et al., 2002)
      Rescued by

      Khc8.70 is rescued by Khc+t7.5

      (Januschke et al., 2002)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Khc8.70
      khc8.70
      (Januschke et al., 2002)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)