FlyBase Allele Report: Dmel\sqz[GAL4]

General Information

Symbol

Dmel\sqz^GAL4

Species

D. melanogaster

Name

FlyBase ID

FBal0150240

Feature type

allele

Associated gene

Dmel\sqz

Associated Insertion(s)

P{GawB}sqz^GAL4

Carried in Construct

Also Known As

sqz-Gal4

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

gene conversion

(Allan et al., 2003)

P-element activity

(Allan et al., 2003)

Progenitor genotype

P{PZ}sqz⁰²¹⁰²

(Allan et al., 2003, Allan et al., 2003)

Associated Insertion(s)

P{GawB}sqz^GAL4

Cytology

Description

The P{PZ} element has been replaced by P{GAL4}.

(Allan et al., 2003)

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 15 -- 17

embryonic thorax | restricted

(Baumgardt et al., 2007)

embryonic stage 15 -- larval stage

apterous-expressing neuron of the lateral cluster of the thorax Ap1

(Baumgardt et al., 2007)

apterous-expressing neuron of the lateral cluster of the thorax Ap4

(Baumgardt et al., 2007)

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal locomotor behavior (with Df(3R)Delta-KX23)

(Allan et al., 2003)

lethal (with Df(3R)Delta-KX23)

(Allan et al., 2003)

Phenotype Manifest In

wing (with Df(3R)Delta-KX23)

(Allan et al., 2003)

Detailed Description

Statement

Reference

Df(3R)Dl-KX23/sqz^GAL4 adults are immotile with a persistent tremor and die within 24 hours. 70% of adults also fail to inflate their wings.

(Allan et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

sqz^GAL4 is rescued by sqz^UAS.cAa/Scer\GAL4^ap-md544

(Allan et al., 2003)

sqz^GAL4 is rescued by sqz^UAS.cAa/Scer\GAL4^sqz-GAL4

(Allan et al., 2003)

sqz^GAL4 is rescued by sqz^UAS.cAa/Scer\GAL4^ap-md544

(Allan et al., 2003)

sqz^GAL4 is rescued by sqz^UAS.cAa/Scer\GAL4^sqz-GAL4

(Allan et al., 2003)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

sqz^GAL4

(Baumgardt et al., 2007, Herrero et al., 2007)

sqz^Gal4

(Benito-Sipos et al., 2010)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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