FB2026_02 , released June 18, 2026
Allele: Dmel\fzsevE3.sevP
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General Information
Symbol
Dmel\fzsevE3.sevP
Species
D. melanogaster
Name
FlyBase ID
FBal0150487
Feature type
allele
Associated gene
Dmel\fz
Associated Insertion(s)
Carried in Construct
P{sevE3.sevP-fz}
Key Links
Transgenic product class
wild_type
(Strutt and Strutt, 2002)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Strutt and Strutt, 2002)
Mutagen
in vitro construct
(Strutt and Strutt, 2002)
Progenitor genotype
Carried in construct
P{sevE3.sevP-fz}
Cytology
Description

Construct: Three copies of a 700 bp sev enhancer fused to a 1 kb sev promoter, drive expression of the fz ORF (including 16 bp upstream and 110 bp downstream UTRs), fused to a tubulin 3' UTR.

(Strutt and Strutt, 2002)
Allele components
Component
Use(s)
Regulatory region(s)
sev
Encoded product / tool
fz
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      fzsevE3.sevP partially rescues Df(3L)fz-GF3b/fz19

      (Strutt and Strutt, 2002)

      fzsevE3.sevP partially rescues Df(3L)fz-GF3b/fz15

      (Strutt and Strutt, 2002)
      Comments

      fzP278L.Act5C.T:Avic\GFP-EGFP together with fzsevE3.SevP.PS, completely rescues the ommatidial polarity of fz15/Df(3L)fz-GF3b flies. fzsevE3.SevP.PS partially rescues the ommatidial polarity phenotype due to fz15/Df(3L)fz-GF3b : 15-25% of ommatidia have inverted dorsal-ventral polarity; 5-10% show anterior-posterior polarity defects; and ommatidia are occasionally mis-rotated. Rescue of anterior-posterior polarity defects and mis-rotation, is more complete at 18oC than at 25oC. fzsevE3.SevP.PS almost completely rescues the ommatidial polarity phenotypes of fz19/Df(3L)fz-GF3b flies (to 97% normal from 40% normal).

      (Strutt and Strutt, 2002)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      fzsevE3.SevP.PS
      fzsevE3.sevP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)