FlyBase Allele Report: Dmel\achi[1]

General Information

Symbol

Dmel\achi¹

Species

D. melanogaster

Name

FlyBase ID

FBal0150568

Feature type

allele

Associated gene

Dmel\achi

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Ayyar et al., 2003)

Progenitor genotype

achi^EP2107

(Ayyar et al., 2003)

Caused by aberration

Df(2R)achi¹

Cytology

Description

Imprecise excision of P{EP}achi^EP2107 has removed all of the proximal portion of achi and some of vis.

(Ayyar et al., 2003)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

achi¹, vis^achi-1 has viable phenotype

(Ayyar et al., 2003)

achi¹, vis^achi-1 has male sterile phenotype

(Ayyar et al., 2003)

achi¹, vis^achi-1 has abnormal meiotic cell cycle phenotype

(Ayyar et al., 2003)

achi¹, vis^Z3922 has viable phenotype

(Ayyar et al., 2003)

achi¹, vis^Z3922 has male sterile phenotype

(Ayyar et al., 2003)

Phenotype Manifest In

Other

Statement

Reference

achi¹, vis^achi-1 has spermatozoon phenotype

(Ayyar et al., 2003)

achi¹, vis^achi-1 has testis phenotype

(Ayyar et al., 2003)

achi¹, vis^Z3922 has spermatozoon phenotype

(Ayyar et al., 2003)

achi¹, vis^Z3922 has testis phenotype

(Ayyar et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

Df(2R)achi¹ homozygotes (which is a deletion that creates two alleles achi¹ and vis^achi-1) are viable. Their males are completely sterile and females crossed to wild-type males exhibit a delay in egg laying. testes from homozygous males have a complete absence of mature sperm. Stages up to late spermatocyte are present but no meiotic stages can be seen. Df(2R)achi¹ testes exhibit a marked defect in the chromatin of mature primary spermatocytes (stages S5 and S6). While these cells are large and have the prominent nucleoli characteristic of this stage, the chromatin is condensed into tight central blobs normally observed only in later meiotic cells.

(Ayyar et al., 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

achi¹

(Mikhaylova et al., 2006)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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