FlyBase Allele Report: Dmel\tum[RNAi.UAS.cSa]

General Information

Symbol

Dmel\tum^RNAi.UAS.cSa

Species

D. melanogaster

Name

FlyBase ID

FBal0150658

Feature type

allele

Associated gene

Dmel\tum

Associated Insertion(s)

Carried in Construct

P{UAS-tum.RNAi.S}

Also Known As

RacGAP50C^RNAi

Key Links

Transgenic product class

RNAi_reagent

(Somers and Saint, 2003)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Somers and Saint, 2003)

Mutagen

in vitro construct

(Somers and Saint, 2003)

Progenitor genotype

Carried in construct

P{UAS-tum.RNAi.S}

Cytology

Description

UAS sequences drive expression of an inverted repeat of nucleotides 248-1125 of the tum ORF.

(Somers and Saint, 2003)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

tum

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal mitotic cell cycle | pupal stage, with Scer\GAL4^en-e16E

(Somers and Saint, 2003)

abnormal planar polarity, with Scer\GAL4^en-e16E

(Somers and Saint, 2003)

increased cell size | pupal stage, with Scer\GAL4^en-e16E

(Somers and Saint, 2003)

Phenotype Manifest In

wing blade posterior compartment, with Scer\GAL4^en-e16E

(Somers and Saint, 2003)

wing hair, with Scer\GAL4^en-e16E

(Somers and Saint, 2003)

Detailed Description

Statement

Reference

Cells in the posterior of pupal wings of RacGAP50C^{dsRNA.Scer\UAS.cSa}; Scer\GAL4^en-e16E animals are abnormally large, and typically binucleate. Each cell often produces multiple wing hairs, and there are minor disruptions in planar polarity.

(Somers and Saint, 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Other

Statement

Reference

Scer\GAL4^en-e16E, pbl^{ΔDH497-549.UAS}, tum^RNAi.UAS.cSa has wing blade posterior compartment phenotype

(Somers and Saint, 2003)

Additional Comments

Genetic Interactions

Statement

Reference

RacGAP50C^{dsRNA.Scer\UAS.cSa}; Scer\GAL4^en-e16E and pbl^{ΔDH497-549.Scer\UAS} ; Scer\GAL4^en-e16E flies show no loss of posterior wing blade, but RacGAP50C^{dsRNA.Scer\UAS.cSa}; pbl^{ΔDH497-549.Scer\UAS}; Scer\GAL4^en-e16E animals lack all or most of this structure.

(Somers and Saint, 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

RacGAP50C^RNAi

(Somers and Saint, 2003)

RacGAP50C^{Scer\UAS.dsRNA}

RacGAP50C^{dsRNA.Scer\UAS.cSa}

tum^RNAi.UAS.cSa

tum^{dsRNA.Scer\UAS.cSa}

tum^{dsRNA.UAS.cSa}

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

Open Close