FB2026_02 , released June 18, 2026
Allele: Dmel\pxbBG01912
Open Close
General Information
Symbol
Dmel\pxbBG01912
Species
D. melanogaster
Name
FlyBase ID
FBal0151619
Feature type
allele
Associated gene
Dmel\pxb
Associated Insertion(s)
P{GT1}pxbBG01912
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Norga et al., 2003)
Progenitor genotype
Associated Insertion(s)
P{GT1}pxbBG01912
Cytology
Description

Insertion is less than 1 kb upstream of the pxb gene.

(Norga et al., 2003)
Allele components
Component
Use(s)
Inserted element
P{GT1}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      pxbBG01912 homozygous males have significantly increased levels of aggression. (P < 0.0001; Male aggression index = 17.3) and show morphological defects in their mushroom bodies including significantly wider alpha-lobes and significanly shorter, wider beta-lobes.

      (Edwards et al., 2009)

      Mutants exhibit a quantitative gain of bristles.

      (Norga et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Precise excision of the P{GT1}pxbBG01912 leads to reversion of the increased aggression phenotype seen in P{GT1}pxbBG01912 males.

      (Edwards et al., 2009)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      pxbBG01912
      Name Synonyms
      Secondary FlyBase IDs
        References (2)