FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\neurBG02542
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General Information
Symbol
Dmel\neurBG02542
Species
D. melanogaster
Name
FlyBase ID
FBal0151694
Feature type
allele
Associated gene
Dmel\neur
Associated Insertion(s)
P{GT1}neurBG02542
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Norga et al., 2003)
Progenitor genotype
Associated Insertion(s)
P{GT1}neurBG02542
Cytology
Description

P{GT1} insertion approximately 70bp upstream of exon 1 of transcripts neur-RA and neur-RB and in the first intron of transcripts neur-RC and neur-RD.

(Rollmann et al., 2008)

Insertion is in the neur gene.

(Norga et al., 2003)
Allele components
Component
Use(s)
Inserted element
P{GT1}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      neurBG02542 homozygous males have significantly decreased levels of aggression. (P < 0.05; Male aggression index = 11.35).

      (Edwards et al., 2009)

      Homozygous flies show no significant change in the number of sternopleural bristles compared to controls.

      Homozygous females show a significant reduction in the number of abdominal bristles compared to controls.

      Mutant flies show a normal behavioural avoidance response to benzaldehyde in an olfactory assay.

      Mutant males and females show a significant reduction in locomotor activity compared to controls.

      The average number of aggressive encounters by males competing for a limited food supply after a period of food deprivation is not significantly different in neurBG02542 males and in controls.

      Gross morphological defects are seen in some of the mushroom bodies of neurBG02542 flies, including shorter and thinner α-lobes and aberrant projections of the α-lobe. The ellipsoid bodies are often disorganised or show morphological defects, such as a ventral open defect. Detailed morphometric analysis reveals that there is a reduction in ellipsoid body surface in neurBG02542 flies compared to controls.

      (Rollmann et al., 2008)

      Mutants exhibit a quantitative gain of bristles.

      (Norga et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      neurBG02542
      (Rollmann et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)