FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\nemyP153
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General Information
Symbol
Dmel\nemyP153
Species
D. melanogaster
Name
FlyBase ID
FBal0151695
Feature type
allele
Associated gene
Dmel\nemy
Associated Insertion(s)
P{lacW}nemyP153
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Kamyshev et al., 2002)
Progenitor genotype
Associated Insertion(s)
P{lacW}nemyP153
Cytology
Description

Insertion within the 5' end of the first exon, within a non-coding portion of the transcription unit.

(Iliadi et al., 2008)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant flies show a significant defect in 3 hour memory (assayed 3 hours after a single training session in the odor-shock paradigm) compared to controls.

      (Iliadi et al., 2008)

      Mutant males show distinct memory deficiency in two courtship conditioning assays. These defects are apparent 0.5 hours after training. The mutant males show an increased level of locomotor activity unrelated to courtship and spend more time in such an element of courtship as pursuit. Mutant flies show subnormal levels of memory performance in an odor-shock classical conditioning assay.

      (Kamyshev et al., 2002)

      While the learning index in wild-type flies persists for at least eight hours at the level reached immediately after completion of training, the learning index in nemyP153 mutants is significantly lower than it is in the wild-type by one hour after training. Complete loss of memory in the males of nemyP153 occurs by eight hours after training.

      (Kamyshev et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      nemyP153 is rescued by Scer\GAL4elav-C155/nemyRA.UAS

      (Iliadi et al., 2008)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Precise excision of the insertion reverts the memory defects of mutant flies.

      (Iliadi et al., 2008)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      nemy153
      (Iliadi et al., 2008)
      nemyP153
      (Bragina et al., 2025, Iliadi et al., 2008, Iliadi et al., 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)