FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\kek1UASp.cGa
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General Information
Symbol
Dmel\kek1UASp.cGa
Species
D. melanogaster
Name
FlyBase ID
FBal0151819
Feature type
allele
Associated gene
Dmel\kek1
Associated Insertion(s)
Carried in Construct
P{UASp-kek1.G}
Key Links
Transgenic product class
wild_type
(Ghiglione et al., 2003)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Ghiglione et al., 2003)
Mutagen
in vitro construct
(Ghiglione et al., 2003)
Progenitor genotype
Carried in construct
P{UASp-kek1.G}
Cytology
Description

UASp regulatory sequences drive expression of kek1.

(Ghiglione et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
kek1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      6% of the eggs (n=112) laid by kek1Scer\UAS.P\T.cGa; Scer\GAL4nos.UTR.T:Hsim\VP16 females are weakly ventralized (partial or total fusion of the dorsal appendages).

      (Ghiglione et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      Scer\GAL4VP16.nanos.UTR, kek1UASp.cGa has dorsal appendage phenotype, enhanceable by grk2B6/grk[+]

      (Ghiglione et al., 2003)

      Scer\GAL4VP16.nanos.UTR, kek1UASp.cGa has egg phenotype, enhanceable by Egfr[+]/Egfrt1

      (Ghiglione et al., 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The penetrance and expressivity of the weak ventralization phenotype seen in eggs laid by kek1Scer\UAS.P\T.cGa; Scer\GAL4nos.UTR.T:Hsim\VP16 females is strongly enhanced by heterozygosity for Egfrt1 (64% of eggs are ventralized, 8% strongly ventralised) or grk2B6.

      (Ghiglione et al., 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      kek1Scer\UAS.P\T.cGa
      kek1UASp.cGa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)