FlyBase Allele Report: Dmel\dgo[269]

General Information

Symbol

Dmel\dgo²⁶⁹

Species

D. melanogaster

Name

FlyBase ID

FBal0152020

Feature type

allele

Associated gene

Dmel\dgo

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Feiguin et al., 2001)

Progenitor genotype

dgo^EP2619

(Feiguin et al., 2001)

Cytology

Description

Imprecise excision of P{EP}EP2619^EP2619 caused a unidirectional deletion beginning at the insertion site and terminating in dgo at ?.

(Feiguin et al., 2001)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal planar polarity

(Jenny et al., 2005, Feiguin et al., 2001)

viable

(Feiguin et al., 2001)

Phenotype Manifest In

ommatidium

(Jenny et al., 2005, Feiguin et al., 2001)

ommatidium (with Df(2R)27)

(Feiguin et al., 2001)

wing hair

(Feiguin et al., 2001)

wing hair (with Df(2R)27)

(Feiguin et al., 2001)

Detailed Description

Statement

Reference

Homozygotes show a weak planar cell polarity phenotype in the eye.

(Jenny et al., 2005)

dgo²⁶⁹ homozygotes have moderately severe planar polarity defects in wing hairs and ommatidia but only mild planar polarity defects in bristles. The eye defects include misrotation and inverted chirality (average 10.4+/-1.6 % of ommatidia) and symmetrical ommatidia (average 6.4+/-2.6 % of ommatidia).

(Feiguin et al., 2001)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

dgo²⁶⁹ has abnormal planar polarity phenotype, enhanceable by dsh¹/dsh[+]

(Jenny et al., 2005)

Other

Statement

Reference

CG15283^GD13108, Scer\GAL4^en-e16E, dgo[+]/dgo²⁶⁹ has abnormal planar polarity phenotype

(Weber et al., 2012)

CG15283^GD13108, Scer\GAL4^en-e16E, Vang^stbm-6/Vang[+], dgo[+]/dgo²⁶⁹ has abnormal planar polarity phenotype

(Weber et al., 2012)

Phenotype Manifest In

Enhanced by

Statement

Reference

dgo²⁶⁹ has ommatidium phenotype, enhanceable by dsh¹/dsh[+]

(Jenny et al., 2005)

Other

Statement

Reference

CG15283^GD13108, Scer\GAL4^en-e16E, dgo[+]/dgo²⁶⁹ has wing hair phenotype

(Weber et al., 2012)

CG15283^GD13108, Scer\GAL4^en-e16E, Vang^stbm-6/Vang[+], dgo[+]/dgo²⁶⁹ has wing hair phenotype

(Weber et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

The weak planar cell polarity phenotype seen in the eyes of dgo²⁶⁹ homozygotes is enhanced by dsh¹/+.

(Jenny et al., 2005)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

269

(Weber et al., 2012)

dgo 269

(Feiguin et al., 2001)

dgo-269

(Feiguin et al., 2001)

dgo²⁶⁹

(Jenny et al., 2005)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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