FlyBase Allele Report: Dmel\RhoGEF64C[EP3322]

General Information

Symbol

Dmel\RhoGEF64C^EP3322

Species

D. melanogaster

Name

FlyBase ID

FBal0152491

Feature type

allele

Associated gene

Dmel\RhoGEF64C

Associated Insertion(s)

P{EP}RhoGEF64C^EP3322

Carried in Construct

Also Known As

EP(3)3322

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(McGovern et al., 2003)

Progenitor genotype

Associated Insertion(s)

P{EP}RhoGEF64C^EP3322

Cytology

Description

Inserted 405bp upstream from the start of the Gef64C first exon.

(McGovern et al., 2003)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:4,692,327..4,692,327 [+]

(Raymond et al., 2004, McGovern et al., 2003)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

viable, with Scer\GAL4^sca-4512

(McGovern et al., 2003)

visible, with Scer\GAL4^GMR.PU

(Raymond et al., 2004)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PU

(Raymond et al., 2004)

larval ventral nerve cord commissure, with Scer\GAL4^sca-4512

(McGovern et al., 2003)

Detailed Description

Statement

Reference

Expression of Gef64C^EP3322 under the control of Scer\GAL4^GMR.PU results in a rough eye phenotype.

(Raymond et al., 2004)

ventral nerve cord commissures in stage 17 Gef64C^EP3322; Scer\GAL4^sca-4512 embryos are fused.

(McGovern et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

RhoGEF64C^EP3322, Scer\GAL4^GMR.PU is a non-enhancer of visible phenotype of Ras85D^N17.UAS, Scer\GAL4^GMR.PU

(Raymond et al., 2004)

NOT Suppressor of

Statement

Reference

RhoGEF64C^EP3322, Scer\GAL4^GMR.PU is a non-suppressor of visible phenotype of Ras85D^N17.UAS, Scer\GAL4^GMR.PU

(Raymond et al., 2004)

Other

Statement

Reference

Cdc42^N17.UAS, RhoGEF64C^EP3322, Scer\GAL4^GMR.PU has lethal | pupal stage phenotype

(Raymond et al., 2004)

Rac1^N17.UAS, RhoGEF64C^EP3322, Scer\GAL4^GMR.PU has lethal | pupal stage phenotype

(Raymond et al., 2004)

RacGAP84C^GAP.UAS, RhoGEF64C^EP3322, Scer\GAL4^GMR.PU has lethal | pupal stage phenotype

(Raymond et al., 2004)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

RhoGEF64C^EP3322, Scer\GAL4^GMR.PU is a non-enhancer of eye phenotype of Ras85D^N17.UAS, Scer\GAL4^GMR.PU

(Raymond et al., 2004)

NOT Suppressor of

Statement

Reference

RhoGEF64C^EP3322, Scer\GAL4^GMR.PU is a non-suppressor of eye phenotype of Ras85D^N17.UAS, Scer\GAL4^GMR.PU

(Raymond et al., 2004)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Gef64C^EP3322

RhoGEF64C^EP3322

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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