FlyBase Allele Report: Dmel\Fas2[G0081]

General Information

Symbol

Dmel\Fas2^G0081

Species

D. melanogaster

Name

FlyBase ID

FBal0152505

Feature type

allele

Associated gene

Dmel\Fas2

Associated Insertion(s)

P{lacW}Fas2^G0081

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Schäfer et al., 1999.3.29)

Progenitor genotype

Associated Insertion(s)

P{lacW}Fas2^G0081

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:4,194,307..4,194,550 [-]

(Peter et al., 2002, Schäfer et al., 1999.3.29, Schäfer et al., 1999.6.15)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

AJ426658

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | larval stage

(Peter et al., 2002)

lethal | prepupal stage

(Peter et al., 2002)

lethal | pupal stage

(Peter et al., 2002)

lethal | recessive

(Schäfer et al., 1999.3.29)

Phenotype Manifest In

Detailed Description

Statement

Reference

Lethality occurs from the third larval instar through to the pupal stage.

(Peter et al., 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Df(2L)let-7-C^KO1, Fas2^G0081, P{W8,let7C^Δmir-let7} has abnormal neuroanatomy phenotype

(Kucherenko et al., 2012)

Phenotype Manifest In

Other

Statement

Reference

Df(2L)let-7-C^KO1, Fas2^G0081, P{W8,let7C^Δmir-let7} has lobe system of adult mushroom body phenotype

(Kucherenko et al., 2012)

Additional Comments

Genetic Interactions

Statement

Reference

Df(2L)let-7-C^KO1/Fas2^G0081 ; P{W8,let-7-C^Δlet-7} animals have defects in the mushroom body α/β lobes: the lobes may appear slim.

(Kucherenko et al., 2012)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

P{lacW} not verified as causing the lethality.

(Schäfer et al., 1999.3.29)

External Crossreferences and Linkouts ( 1 )

Crossreferences

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

AJ426658

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Fas2^G0081

(Kucherenko et al., 2012)

l(1)G0081

(Peter et al., 2002)

l(1)G0081^G0081

(Schäfer et al., 1999.3.29, Schäfer et al., 1999.6.15)

Name Synonyms

Secondary FlyBase IDs

FBal0096828

References (4)

Report Sections

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