FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Act5CBG01299
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General Information
Symbol
Dmel\Act5CBG01299
Species
D. melanogaster
Name
FlyBase ID
FBal0152801
Feature type
allele
Associated gene
Dmel\Act5C
Associated Insertion(s)
P{GT1}Act5CBG01299
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Norga et al., 2003)
Progenitor genotype
Associated Insertion(s)
P{GT1}Act5CBG01299
Cytology
Description

Insertion is in the Act5C gene.

(Norga et al., 2003)
Allele components
Component
Use(s)
Inserted element
P{GT1}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Act5CBG01299 homozygous males have significantly decreased levels of aggression. (P < 0.0001; Male aggression index = 3.6). The mushroom body alpha-lobes in these animals are significantly longer (relative to overall brain size) than wild-type (p < 0.05)

      (Edwards et al., 2009)

      Mutants exhibit a quantitative loss of bristles.

      (Norga et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Precise excision of the P{GT1}Act5CBG01299 leads to reversion of the decreased aggression phenotype seen in P{GT1}Act5CBG01299 homozygotes.

      (Edwards et al., 2009)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Act5CBG01299
      Name Synonyms
      Secondary FlyBase IDs
        References (2)