FlyBase Allele Report: Dmel\lbm[EY02692]

General Information

Symbol

Dmel\lbm^EY02692

Species

D. melanogaster

Name

FlyBase ID

FBal0155042

Feature type

allele

Associated gene

Dmel\lbm

Associated Insertion(s)

P{EPgy2}lbm^EY02692

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Gene Disruption Project members, 2001-)

Progenitor genotype

Associated Insertion(s)

P{EPgy2}lbm^EY02692

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{EPgy2}

misexpression element

Regulatory region(s)

UASp

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:7,049,820..7,049,820 [+]

(Yang et al., 2013, Franciscovich et al., 2008, Gene Disruption Project members, 2001-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4^elav-C155

(Franciscovich et al., 2008)

Phenotype Manifest In

synapse, with Scer\GAL4^elav-C155

(Franciscovich et al., 2008)

Detailed Description

Statement

Reference

Expression of lbm^EY02692 in differentiated post-mitotic neurons under the control of Scer\GAL4^elav-C155 suppresses synaptic growth.

(Franciscovich et al., 2008)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

lbm^EY02692, Scer\GAL4^hs.2sev is a suppressor of increased cell death phenotype of Mmus\Gria1^Lc.UAS, Scer\GAL4^hs.2sev

(Yang et al., 2013)

Phenotype Manifest In

Suppressor of

Statement

Reference

lbm^EY02692, Scer\GAL4^hs.2sev is a suppressor of eye phenotype of Mmus\Gria1^Lc.UAS, Scer\GAL4^hs.2sev

(Yang et al., 2013)

lbm^EY02692/Scer\GAL4^ey.3.5.Exel is a suppressor of eye phenotype of Scer\GAL4^ey.3.5.Exel, kay^Fbz.UAS

(Franciscovich et al., 2008)

Scer\GAL4^elav-C155/lbm^EY02692 is a suppressor | partially of synapse phenotype of Scer\GAL4^elav-C155, kay^Fbz.UAS

(Franciscovich et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of lbm^EY02692 suppresses the small eye phenotype associated with kay^Fbz.Scer\UAS, when both are expressed under the control of Scer\GAL4^ey.3.5.Exel.

Co-expression of lbm^EY02692 with kay^Fbz.Scer\UAS in differentiated post-mitotic neurons under the control of Scer\GAL4^elav-C155 partially suppresses the small synapse phenotype found in kay^Fbz.Scer\UAS mutants.

(Franciscovich et al., 2008)

Xenogenetic Interactions

Statement

Reference

A lbm^EY02692 background rescues the reduced adult eye size phenotype found in Scer\GAL4^hs.2sev->Mmus\Gria1^Lc.Scer\UAS flies.

(Yang et al., 2013)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

15583

y¹ w^67c23; P{EPgy2}lbm^EY02692

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

lbm^EY02692

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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