FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\encunspecified
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General Information
Symbol
Dmel\encunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0155329
Feature type
allele
Associated gene
Dmel\enc
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

    (FlyBase Curators, 2025-)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Mutant females raised at 25oC produce 55% of egg chambers with 32 cells. At 29oC, 70% of egg chambers have 32 cells.

        (Ohlmeyer and Schupbach, 2003)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhanced by
        Suppressed by
        NOT suppressed by
        Statement
        Reference

        encunspecified has abnormal mitotic cell cycle phenotype, non-suppressible by CycA[+]/CycAunspecified

        (Ohlmeyer and Schupbach, 2003)
        Phenotype Manifest In
        Enhanced by
        Statement
        Reference

        encunspecified has egg chamber phenotype, enhanceable by Ubc2k13206/UbcD2[+]

        (Ohlmeyer and Schupbach, 2003)

        encunspecified has egg chamber phenotype, enhanceable by effunspecified/eff[+]

        (Ohlmeyer and Schupbach, 2003)

        encunspecified has egg chamber phenotype, enhanceable by lin19[+]/Cul1unspecified

        (Ohlmeyer and Schupbach, 2003)
        Suppressed by
        Statement
        Reference

        encunspecified has egg chamber phenotype, suppressible by CycE[+]/CycEunspecified

        (Ohlmeyer and Schupbach, 2003)

        encunspecified has egg chamber phenotype, suppressible by ruxhs.PT

        (Ohlmeyer and Schupbach, 2003)
        NOT suppressed by
        Statement
        Reference

        encunspecified has egg chamber phenotype, non-suppressible by CycA[+]/CycAunspecified

        (Ohlmeyer and Schupbach, 2003)
        Suppressor of
        Statement
        Reference

        encunspecified is a suppressor of eye phenotype of Scer\GAL4GMR.PF, nejΔBHQ.UAS

        (Anderson et al., 2005)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The extra mitotic division phenotype seen in the egg chambers of encunspecified females at 25oC is not suppressed by CycAunspecified/+. The extra mitotic division phenotype seen in the egg chambers of encunspecified females at 25oC is partially suppressed by ruxhs.PT; only 25% of egg chambers contain 32 cells. This suppression of encunspecified by ruxhs.PT is not significantly altered if the females also carry CycAunspecified/+. The extra mitotic division phenotype seen in the egg chambers of encunspecified females at 29oC is suppressed from 70% to 10% by CycEunspecified/+. The extra mitotic division phenotype seen in the egg chambers of encunspecified females is enhanced by one copy of lin19unspecified, UbcD2k13206 or effunspecified at both room temperature and 25oC; the frequency of egg chambers containing 32 cells is increased in the double mutant females.

        (Ohlmeyer and Schupbach, 2003)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        encunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (3)