FlyBase Allele Report: Dmel\dl[UY2278]

General Information

Symbol

Dmel\dl^UY2278

Species

D. melanogaster

Name

FlyBase ID

FBal0155396

Feature type

allele

Associated gene

Dmel\dl

Associated Insertion(s)

P{Mae-UAS.6.11}dl^UY2278

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Nicolai et al., 2003)

Progenitor genotype

Associated Insertion(s)

P{Mae-UAS.6.11}dl^UY2278

Cytology

Description

Insertion site maps to -311bp of the known/supposed transcription start site.

(Nicolai et al., 2003)

Allele components

Component

Use(s)

Inserted element

P{Mae-UAS.6.11}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Scer\GAL4^7B

(Nicolai et al., 2003)

abnormal neuroanatomy, with Scer\GAL4^ey-OK107

(Nicolai et al., 2003)

visible | temperature conditional, with Scer\GAL4^sca-537.4

(Ayyar et al., 2007)

Phenotype Manifest In

adult mushroom body, with Scer\GAL4^7B

(Nicolai et al., 2003)

adult mushroom body, with Scer\GAL4^ey-OK107

(Nicolai et al., 2003)

Kenyon cell, with Scer\GAL4^7B

(Nicolai et al., 2003)

Kenyon cell, with Scer\GAL4^ey-OK107

(Nicolai et al., 2003)

macrochaeta | ectopic | temperature conditional, with Scer\GAL4^sca-537.4

(Ayyar et al., 2007)

macrochaeta | temperature conditional, with Scer\GAL4^sca-537.4

(Ayyar et al., 2007)

mesonotum | temperature conditional, with Scer\GAL4^sca-537.4

(Ayyar et al., 2007)

mushroom body & axon, with Scer\GAL4^7B

(Nicolai et al., 2003)

mushroom body & axon, with Scer\GAL4^ey-OK107

(Nicolai et al., 2003)

Detailed Description

Statement

Reference

Expression of dl^UY2278 under the control of Scer\GAL4^sca-537.4 at 25[o]C results in loss of bristles over much of the notum, although the loss is greater in the lateral notum. Expression of dl^UY2278 under the control of Scer\GAL4^sca-537.4 at 18[o]C results in the generation of ectopic bristles on the medial notum in the dorsocentral and scutellar regions.

(Ayyar et al., 2007)

When expression is driven by Scer\GAL4^7B or Scer\GAL4^OK107, dl^UY2278 shows a mushroom body Class II phenotype; neuron number defects plus axonal growth and guidance defects. Axons seem defasciculated.

(Nicolai et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

7350

y¹ w^67c23; P{Mae-UAS.6.11}dl^UY2278

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

dl^UY2278

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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