FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\SxlUAS.cHa
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General Information
Symbol
Dmel\SxlUAS.cHa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Horabin
FlyBase ID
FBal0155776
Feature type
allele
Associated gene
Dmel\Sxl
Associated Insertion(s)
Carried in Construct
P{UAS-Sxl.H}
Also Known As
UAS-Sxl
Key Links
Transgenic product class
wild_type
(Horabin et al., 2003)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Horabin et al., 2003)
Mutagen
in vitro construct
(Horabin et al., 2003)
Progenitor genotype
Carried in construct
P{UAS-Sxl.H}
Cytology
Description

UAS sequences drive expression of Sxl.

(Horabin et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Sxl
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When SxlScer\UAS.cHa is driven by Scer\GAL4dpp.blk1 no males are recovered. Eclosed females are found to have varying degrees of leg defects ranging from wild-type to a shortening of the more distal regions. All wings show a reduction in the area between wing veins L3 and L4, while the rest of the wing looks normal. Additionally the hairs at the wing margin between wing veins L3 and L4 show the characteristics of the anterior rather than the posterior compartment.

      (Horabin et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      SxlUAS.cHa/Scer\GAL4elav.PZ is a suppressor of visible | somatic clone phenotype of elav5

      (Zaharieva et al., 2015)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      SxlUAS.cHa/Scer\GAL4elav.PZ is a suppressor of eye | somatic clone phenotype of elav5

      (Zaharieva et al., 2015)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of SxlScer\UAS.cHa under the control of Scer\GAL4elav.PZ does not rescue the small eye phenotype seen in elav5 mutant eyes (generated by expressing elavelav.PZ and excising the FRT cassette in the eye primordium).

      (Zaharieva et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      SxlScer\UAS.cHa
      SxlUAS.cHa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Horabin
      (Horabin et al., 2003)
      Secondary FlyBase IDs
        References (3)