FB2026_02 , released June 18, 2026
Allele: Dmel\EP2190EP2190
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General Information
Symbol
Dmel\EP2190EP2190
Species
D. melanogaster
Name
FlyBase ID
FBal0156601
Feature type
allele
Associated gene
EP2190
Associated Insertion(s)
P{EP}EP2190EP2190
Carried in Construct
Also Known As
EP(2)2190
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{EP}EP2190EP2190
    Cytology
    Description

    The orientation of the P{EP}EP2190EP2190 element is opposite to the direction of CG10927 transcription.

    (Shulman and Feany, 2003)
    Allele components
    Component
    Use(s)
    Inserted element
    P{EP}
    Regulatory region(s)
    UAS
    Mutations Mapped to the Genome
    Curation Data
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 1 )
        Disease
        Interaction
        References
        exacerbates  tauopathy
        modeled by Hsap\MAPTV337M.UAS
        (Shulman and Feany, 2003)
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Expression via Scer\GAL4fkh.PH results in a strongly penetrant positioning ('hook') phenotype in the embryonic salivary gland.

        (Maybeck and Röper, 2009)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhancer of
        NOT Enhancer of
        Statement
        Reference

        EP2190EP2190, Scer\GAL4GMR.PF is a non-enhancer of visible phenotype of Hsap\ATXN182.UAS, Scer\GAL4GMR.PF

        (Shulman and Feany, 2003)
        NOT Suppressor of
        Statement
        Reference

        EP2190EP2190, Scer\GAL4GMR.PF is a non-suppressor of visible phenotype of Hsap\ATXN182.UAS, Scer\GAL4GMR.PF

        (Shulman and Feany, 2003)
        Phenotype Manifest In
        Enhancer of
        NOT Enhancer of
        Statement
        Reference

        EP2190EP2190, Scer\GAL4GMR.PF is a non-enhancer of eye phenotype of Hsap\ATXN182.UAS, Scer\GAL4GMR.PF

        (Shulman and Feany, 2003)
        NOT Suppressor of
        Statement
        Reference

        EP2190EP2190, Scer\GAL4GMR.PF is a non-suppressor of eye phenotype of Hsap\ATXN182.UAS, Scer\GAL4GMR.PF

        (Shulman and Feany, 2003)
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference

        The rough eye phenotype caused by expression of Hsap\MAPTV337M.Scer\UAS under the control of Scer\GAL4GMR.PF is enhanced by EP2190EP2190.

        (Shulman and Feany, 2003)
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        Comments
        Comments

        Precise excision of the P{EP} element reverts the modifying effect of EP2190EP2190 on the rough eye phenotype caused by expression of Hsap\MAPTV337M.Scer\UAS under the control of Scer\GAL4GMR.PF.

        (Shulman and Feany, 2003)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        EP2190EP2190
        Name Synonyms
        Secondary FlyBase IDs
          References (2)