Expression of two copies of the Hsap\BoatScer\UAS.T:Zzzz\FLAG transgene, under the control of Scer\GAL4GMR.PF, suppresses the Scer\GAL4GMR.PF>Hsap\ATX182.Scer\UAS-induced eye phenotype. These flies show a restoration of bristle formation, pigmentation, and overall eye structure. However, there is also a gain-of-function phenotype, with rescued eyes showing thicker and longer bristles.
The rough eye phenotype seen Hsap\ATX182.Scer\UAS, Scer\GAL4GMR.PF animals is enhanced by SmrBG01648, resulting in a glazed eye surface, severely disorganised ommatidia, and most prominently loss of bristles. The rough eye phenotype seen Hsap\ATX182.Scer\UAS, Scer\GAL4GMR.PF animals is suppressed by Dp(1;Y)BSC5 or DnaJ-1Scer\UAS.cKa.