UAS regulatory sequences drive expression of mutant form of Hsap\ATXN1 which has an expanded repeat length encoding 82 glutamine residues.
Expression of Hsap\ATX182.Scer\UAS, under the control of Scer\GAL4GMR.PF, results in a severely deformed eye phenotype. The ridge along the dorsal-ventral axis of the eye consistently displays the most severe defects; the eye surface is prominently glazed; there is a loss of bristles and pigmentation; ommatidia are disordered; photoreceptors suffer degeneration. Coexpression of Hsap\ATX182.Scer\UAS and Hsap\ATX10Q.Scer\UAS.T:Zzzz\FLAG, under the control of Scer\GAL4GMR.PF, causes a more severe eye phenotype, in which eye structure is collapsed and photoreceptors are severely degenerated.
Flies expressing Hsap\ATX182.Scer\UAS under the control of Scer\GAL4GMR.PF show severe disruption of the retinal structure.
Expression of Hsap\ATX182.Scer\UAS under the control of Scer\GAL4GMR.PF results in a retinal degeneration phenotype.
Expression of Hsap\ATX182.Scer\UAS under the control of Scer\GAL4Cha.7.4 results in a brain degeneration phenotype, approximately 50% of cholinergic neurons of the lamina degenerate after 30 days.
When Hsap\ATX182.Scer\UAS is driven by Scer\GAL4hs.PB (without heat shock) expression is seen in the salivary gland. This expression is detrimental to salivary gland development. Late third instar larvae display cellular deformations, including a significant reduction in cell volume and a notable disarray in tissue organisation. When Hsap\ATX182.Scer\UAS is driven by Scer\GAL4GMR.PF a rough eye phenotype is seen.
Expression of Hsap\ATX182.Scer\UAS under the control of Scer\GAL4GMR.PF results in a slightly rough and depigmented eye.
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, enhanceable by CG7231EP2510, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye color defective phenotype, enhanceable by CG7231EP2510, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, enhanceable by Atx2EP3145, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye color defective phenotype, enhanceable by Atx2EP3145, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by EP639EP2437, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by Orct2EP3569, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by TaoEP1455, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by CG3735EP2311, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by Fem-1EP2504, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by Gbs-70EEP3518, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by EP1072EP1072/Orct2EP1072, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by EP2190EP2190, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by Fmr1EP3517, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by aopEP2500, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by cdiEP3319, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by chbEP3403, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by cherEP3715, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by dallyEP581, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by fryEP326, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by garzEP2028, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by par-1EP899, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by stgEP1213, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by Diap1EP3308, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by tweEP613, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by wdbEP3559, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-enhanceable by wunEP2208, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by EP639EP2437, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by Orct2EP3569, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by TaoEP1455, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by CG3735EP2311, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by Fem-1EP2504, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by Gbs-70EEP3518, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by EP1072EP1072/Orct2EP1072, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by EP2190EP2190, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by Fmr1EP3517, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by aopEP2500, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by cdiEP3319, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by chbEP3403, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by cherEP3715, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by dallyEP581, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by fryEP326, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by garzEP2028, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by par-1EP899, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by stgEP1213, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by Diap1EP3308, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by tweEP613, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by wdbEP3559, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has visible phenotype, non-suppressible by wunEP2208, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
CG7231EP2510, Hsap\ATXN182.UAS, Scer\GAL4ChAT.7.4 has lethal phenotype
Atx2UAS.cSa, Hsap\ATXN182.UAS, Scer\GAL4ChAT.7.4 has lethal phenotype
Atx2EP3145, Hsap\ATXN182.UAS, Scer\GAL4ChAT.7.4 has lethal phenotype
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has retina phenotype, enhanceable by CG7231EP2510, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has retina phenotype, enhanceable by Hsc70-4K71S.UAS, Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has retina phenotype, enhanceable by Sirt1EP2300, Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has retina phenotype, enhanceable by taraEP3463, Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has retina phenotype, enhanceable by pumEP3461, Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has retina phenotype, enhanceable by Atx2UAS.cSa, Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has retina phenotype, enhanceable by Atx2EP3145, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has interommatidial bristle phenotype, enhanceable by SmrBG01648, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has ommatidium phenotype, enhanceable by SmrBG01648, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, enhanceable by SmrBG01648, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, enhanceable by Atx2EP3145, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has pigment cell phenotype, enhanceable by Atx2EP3145, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, enhanceable by CG7231EP2510, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has pigment cell phenotype, enhanceable by CG7231EP2510, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4ChAT.7.4 has adult brain phenotype, non-enhanceable by Hsc70-4K71S.UAS, Scer\GAL4ChAT.7.4
Hsap\ATXN182.UAS, Scer\GAL4ChAT.7.4 has adult brain phenotype, non-enhanceable by Sirt1EP2300, Scer\GAL4ChAT.7.4
Hsap\ATXN182.UAS, Scer\GAL4ChAT.7.4 has adult brain phenotype, non-enhanceable by taraEP3463, Scer\GAL4ChAT.7.4
Hsap\ATXN182.UAS, Scer\GAL4ChAT.7.4 has adult brain phenotype, non-enhanceable by pumEP3461, Scer\GAL4ChAT.7.4
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by EP639EP2437, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by Orct2EP3569, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by TaoEP1455, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by CG3735EP2311, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by Fem-1EP2504, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by Gbs-70EEP3518, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by EP1072EP1072/Orct2EP1072, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by EP2190EP2190, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by Fmr1EP3517, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by aopEP2500, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by cdiEP3319, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by chbEP3403, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by cherEP3715, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by dallyEP581, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by fryEP326, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by garzEP2028, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by par-1EP899, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by stgEP1213, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by Diap1EP3308, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by tweEP613, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by wdbEP3559, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-enhanceable by wunEP2208, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS has pigment cell phenotype, suppressible by Hsap\ATXN1LUAS.Tag:FLAG/Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, suppressible by Hsap\ATXN1LUAS.Tag:FLAG, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has interommatidial bristle phenotype, suppressible by Hsap\ATXN1LUAS.Tag:FLAG, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has retina phenotype, suppressible by Hsap\ATXN3fl.Q27.UAS.Tag:MYC, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has retina phenotype, suppressible by DnaJ-1UAS.cKa, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has retina phenotype, suppressible by Hsap\HSPA1LUAS.cWa, Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has retina phenotype, suppressible by BacA\p35UAS.cUa, Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4ChAT.7.4 has adult brain phenotype, suppressible by Hsap\HSPA1LUAS.cWa, Scer\GAL4ChAT.7.4
Hsap\ATXN182.UAS, Scer\GAL4ChAT.7.4 has adult brain phenotype, suppressible by BacA\p35UAS.cUa, Scer\GAL4ChAT.7.4
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has retina phenotype, suppressible by Diap1UAS.cLa, Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4ChAT.7.4 has adult brain phenotype, suppressible by DnaJ-1UAS.cKa, Scer\GAL4ChAT.7.4
Hsap\ATXN182.UAS, Scer\GAL4ChAT.7.4 has adult brain phenotype, suppressible by Diap1UAS.cLa, Scer\GAL4ChAT.7.4
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, suppressible by DnaJ-1UAS.cKa, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has interommatidial bristle phenotype, suppressible by DnaJ-1UAS.cKa, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has ommatidium phenotype, suppressible by DnaJ-1UAS.cKa, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, suppressible by Dp(1;Y)BSC5, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has interommatidial bristle phenotype, suppressible by Dp(1;Y)BSC5, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has ommatidium phenotype, suppressible by Dp(1;Y)BSC5, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4ChAT.7.4 has adult brain phenotype, non-suppressible by Hsc70-4K71S.UAS, Scer\GAL4ChAT.7.4
Hsap\ATXN182.UAS, Scer\GAL4ChAT.7.4 has adult brain phenotype, non-suppressible by Sirt1EP2300, Scer\GAL4ChAT.7.4
Hsap\ATXN182.UAS, Scer\GAL4ChAT.7.4 has adult brain phenotype, non-suppressible by taraEP3463, Scer\GAL4ChAT.7.4
Hsap\ATXN182.UAS, Scer\GAL4ChAT.7.4 has adult brain phenotype, non-suppressible by pumEP3461, Scer\GAL4ChAT.7.4
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by EP639EP2437, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by Orct2EP3569, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by TaoEP1455, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by CG3735EP2311, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by Fem-1EP2504, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by Gbs-70EEP3518, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by EP1072EP1072/Orct2EP1072, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by EP2190EP2190, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by Fmr1EP3517, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by aopEP2500, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by cdiEP3319, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by chbEP3403, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by cherEP3715, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by dallyEP581, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by fryEP326, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by garzEP2028, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by par-1EP899, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by stgEP1213, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by Diap1EP3308, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by tweEP613, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by wdbEP3559, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Hsap\ATXN182.UAS, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF has eye phenotype, non-suppressible by wunEP2208, Scer\GAL4GMR.PF/Scer\GAL4GMR.PF
Expression of two copies of the Hsap\BoatScer\UAS.T:Zzzz\FLAG transgene, under the control of Scer\GAL4GMR.PF, suppresses the Scer\GAL4GMR.PF>Hsap\ATX182.Scer\UAS-induced eye phenotype. These flies show a restoration of bristle formation, pigmentation, and overall eye structure. However, there is also a gain-of-function phenotype, with rescued eyes showing thicker and longer bristles.
The retinal disruption seen in flies expressing Hsap\ATX182.Scer\UAS under the control of Scer\GAL4GMR.PF is suppressed by co-expression of Hsap\MJDfl.Q27.Scer\UAS.T:Hsap\MYC.
The rough eye phenotype seen Hsap\ATX182.Scer\UAS, Scer\GAL4GMR.PF animals is enhanced by SmrBG01648, resulting in a glazed eye surface, severely disorganised ommatidia, and most prominently loss of bristles. The rough eye phenotype seen Hsap\ATX182.Scer\UAS, Scer\GAL4GMR.PF animals is suppressed by Dp(1;Y)BSC5 or DnaJ-1Scer\UAS.cKa.
Co-expression of CG7231EP2510 or Atx2EP3145 enhances the eye phenotype caused by expression of Hsap\ATX182.Scer\UAS under the control of Scer\GAL4GMR.PF; loss of eye pigmentation is enhanced and necrotic black spots are induced.